HSMR2022: THE 14TH HAMLYN SYMPOSIUM ON MEDICAL ROBOTICS
PROGRAM FOR TUESDAY, JUNE 28TH
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08:00-08:30Coffee & Registration
08:30-09:30 Session 13: Surgical Guidance
Chairs:
Kevin Cleary (Chlidren's National Medical Center, United States)
Stefanie Speidel (National Center for Tumor Diseases Dresden, Germany)
08:30
Martina Favaretto (Politecnico di Milano, Italy)
Aldo Marzullo (University of Calabria, Italy)
Elena De Momi (Politecnico di Milano, Italy)
Studying the Usability of Forbidden Region Virtual Fixtures for Safer Robotic Assisted Minimally Invasive Surgery
08:42
Thomas Fuchs (Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany, Germany)
Eleni Felinska (Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany, Germany)
Alexandros Kogkas (Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK, UK)
George Mylonas (Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK, UK)
Beat Müller-Stich (Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany, Germany)
Felix Nickel (Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany, Germany)
ISurgeon: Augmented Reality Telestration for Improved Surgical Training
PRESENTER: Thomas Fuchs
08:54
Zeyu Wang (The Hamlyn Centre/ Dept of Surgery and Cancer, Imperial College London, UK)
Junhong Chen (The Hamlyn Centre/ Dept of Surgery and Cancer, Imperial College London, UK)
Ruiyang Zhang (The Hamlyn Centre/ Dept of Surgery and Cancer, Imperial College London, UK)
Benny Lo (The Hamlyn Centre/ Dept of Surgery and Cancer, Imperial College London, UK)
The Design of a Biomimetic Whisker-Based System for Clinical Gastrointestinal Diseases Screening
PRESENTER: Zeyu Wang
09:06
Rema Daher (Imperial College London, UK)
Connah Kendrick (Manchester Metropolitan University, UK)
Moi Hoon Yap (Manchester Metropolitan University, UK)
Daniel Leff (Imperial College London, UK)
Stamatia Giannarou (Imperial College London, UK)
Vision-Based Robot Localisation for Ductoscopic Navigation
PRESENTER: Rema Daher
09:18
David Black (University of British Columbia, Canada)
Septimiu Salcudean (University of British Columbia, Canada)
A Mixed Reality System for Human Teleoperation in Tele-Ultrasound
PRESENTER: David Black
09:30-10:15 Session 14: Prof John Skinner, "The Adoption of Robotic Technology for Orthopaedic Surgery in Healthcare Systems"

Professor of Orthopaedic Surgery, University College London

Abstract: This lecture will review the current trends and use of surgical robots in orthopaedic practice. Clinical outcomes and results will be discussed alongside the challenges and obstacles to adoption of innovative robot assisted surgical solutions. The introduction and dissemination of robotic surgery can be costly and difficult to justify initially, particularly in universal healthcare systems. This can hamper widespread use ahead of the accumulation of long term outcome data.

Robots are popular with patients and increasingly so with surgeons. Professor Skinner will give an overview of these issues along with some ideas on the necessary governance, data collection requirements and safeguards that will be essential for the safe and responsible adoption of this exciting technology.

Biography

Professor John A Skinner MBBS, FRCS, FRCS(Orth) – is Professor of Orthopaedic surgery at University College London and Consultant Orthopaedic Surgeon at the Royal National Orthopaedic Hospital, Stanmore (RNOH). He is President of the British Orthopaedic Association. He sits on the Council of the Royal College of Surgeons of England and chairs the Future Surgeons Forum.

He is a hip and knee arthroplasty surgeon and is the Director of Research and Innovation at the Royal National Orthopaedic Hospital. He was awarded an orthopaedic American British Canadian Travelling Fellowship and is a member of the International Hip Society. He has served as President of the British Hip Society and worked on the NICE guideline committee for joint replacement surgery. He jointly established the London Implant Retrieval Centre in 2007, which has collected 8000 failed orthopaedic implants and has published 130 papers on this subject, including reasons for failure. He provided clinical leadership on metal bearing hips for patients and surgeons and chaired the UK MHRA Expert Advisory Committees on Metal bearing hips for 10 years. This work contributed to advice that is followed worldwide and applies to 1.5 million patients with metal bearing hips. He has advised the Federal Drug Administration (FDA) USA on matters related to Hip Arthroplasty surgery. He has worked on custom CAD CAM arthroplasty implant design, surgical planning and patient specific instrument design. He has introduced 4 surgical robotic systems at the RNOH for arthroplasty and spine surgery. His Research interests focus on optimising outcomes for patients undergoing joint replacement surgery.

Chair:
Ferdinando Rodriguez Y Baena (Imperial College)
10:15-10:45Coffee Break
10:45-12:45 Session 15: Neurosurgery
Chairs:
William Anderson (Johns Hopkins University School of Medicine, United States)
Pierre Dupont (Harvard University, United States)
10:45
Alistair Weld (Imperial College London, UK)
Michael Dyck (Technical University of Munich, Germany)
Julian Klodmann (Technical University of Munich, Germany)
Giulio Anichini (Imperial College London, UK)
Luke Dixon (Imperial College London, UK)
Sophie Camp (Imperial College London, UK)
Alin Albu-Schäffer (Technical University of Munich, Germany)
Stamatia Giannarou (Imperial College London, UK)
Collaborative Robotic Ultrasound Tissue Scanning for Surgical Resection Guidance in Neurosurgery
PRESENTER: Michael Dyck
10:57
Nicholas Posselli (University of Utah, United States)
Paul Bernstein (Moran Eye Center, University of Utah, United States)
Jake Abbott (University of Utah, United States)
Head-Mounting Surgical Robots for Passive Motion Compensation
11:09
Anthony Gunderman (Georgia Institute of Technology, United States)
Saikat Sengupta (Vanderbilt University Medical Center, United States)
Dimitri Sigounas (George Washington University, United States)
Kevin Cleary (Children's National Hospital, United States)
Yue Chen (Georgia Institute of Technology, United States)
Towards an MRI-Conditional Robot for Intracerebral Hemorrhage Evacuation
PRESENTER: Kevin Cleary
11:21
Pierre Dupont (Boston Children's Hospital / Harvard Medical School, United States)
Karl Price (Boston Children's Hospital / Harvard Medical School, United States)
Joseph Peine (Boston Children's Hospital / Harvard Medical School, United States)
Margherita Mencattelli (Boston Children's Hospital / Harvard Medical School, United States)
Ashkan Pourkand (Boston Children's Hospital / Harvard Medical School, United States)
Thomas Looi (Sick Kids Hospital, Canada)
James Drake (Sick Kids Hospital, Canada)
Yash Chitalia (Boston Children's Hospital / Harvard Medical School, United States)
Bimanual Endoscopic Robot for Neurosurgery
PRESENTER: Pierre Dupont
11:33
Ayhan Aktas (Imperial College London, UK)
Ali Anil Demircali (Imperial College London, UK)
Riccardo Secoli (Imperial College London, UK)
Burak Temelkuran (Imperial College London, UK)
Ferdinando M Rodriguez Y Baena (Imperial College London, UK)
Towards a Procedure Optimised Steerable Microcatheter for Neurosurgical Laser Ablation
PRESENTER: Ayhan Aktas
11:45
Timothy A. Brumfiel (Medical Robotics and Automation (RoboMed) Laboratory, United States)
Kent K. Yamamoto (Medical Robotics and Automation (RoboMed) Laboratory, United States)
Asif Rashid (George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, United States)
Akiyuki Shigematsu (Medical Robotics and Automation (RoboMed) Laboratory, Japan)
Coley Chapman (George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, United States)
Shreyes N. Melkote (George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, United States)
Joshua J. Chern (Children's Healthcare of Atlanta, United States)
Jaydev P. Desai (Medical Robotics and Automation (RoboMed) Laboratory, United States)
Design of a Meso-Scale Grasper for Robotic Pediatric Neuroendoscope Tool
PRESENTER: Jaydev P. Desai
11:57
Daniel Esser (Vanderbilt University, United States)
John Peters (Vanderbilt University, United States)
Abby Grillo (Vanderbilt University, United States)
Sarah Garrow (Vanderbilt University, United States)
Tyler Ball (Vanderbilt University Medical Center, United States)
Robert Naftel (Vanderbilt University Medical Center, United States)
Dario Englot (Vanderbilt University Medical Center, United States)
Joseph Neimat (University of Louisville, United States)
Will Grissom (Vanderbilt University, United States)
Eric Barth (Vanderbilt University, United States)
Robert Webster III (Vanderbilt University, United States)
Robotic Curvilinear Laser Thermal Therapy Probe for Transforamenal Hippocampotomy
PRESENTER: Daniel Esser
12:09
Jin Seob Kim (Johns Hopkins University, United States)
Ryan Fischer (University of Miami, United States)
Iahn Cajigas (University of Miami, United States)
Michael Ivan (University of Miami, United States)
Doyoung Chang (University of Miami, United States)
A Steerable Guide for MRI-Guided Laser Interstitial Thermal Therapy
PRESENTER: Michael Ivan
12:21
Derick Sivakumaran (Magnebotix AG, Switzerland)
Fabian Christopher Landers (ETH Zürich, Switzerland)
Quentin Boehler (ETH Zurich, Switzerland)
Christophe Chautems (ETH Zurich, Switzerland)
Salvador Pané (ETH Zurich, Switzerland)
Bradley J. Nelson (ETH Zurich, Switzerland)
In Vitro Navigation of a Magnetic Sphere Using a Model Predictive Controller for Neurovascular Targeted Drug Delivery Applications
12:33
Hrishikesh Raghuram (University of Toronto, Canada)
Benjamin Keunen (The Hospital for Sick Children, Canada)
Nathan Soucier (University of Toronto, Canada)
Thomas Looi (The Hospital for Sick Children, Canada)
Samuel Pichardo (University of Calgary, Canada)
Adam Waspe (The Hospital for Sick Children, Canada)
James Drake (The Hospital for Sick Children, Canada)
An MRI Compatible MR-Guided High-Intensity Focused Ultrasound Neonatal Neurosurgery Platform for Intraventricular Hemorrhage
12:45-13:45Lunch Break
13:45-14:30 Session 16: Poster Teasers 2
Chair:
Ana Cruz Ruiz (Imperial College, UK)
13:45
Amir Szold (Assia Medical Group, Israel)
The Fulcrum Effect in the Control of Electromechanical Articulated Laparoscopic Instruments
13:47
Alessandro Casella (Politecnico di Milano, Istituto Italiano di Tecnologia, Italy)
Gaia Romana De Paolis (Politecnico di Milano, Italy)
Elena De Momi (Politecnico di Milano, Italy)
Dario Paladini (Istituto Giannina Gaslini, Italy)
Sara Moccia (The Biorobotic Insitute, Sant'Anna, Italy)
Leonardo Mattos (Istituto Italiano di Tecnologia, Italy)
Inexact Multi-Task Learning for Fetal Anastomoses Detection
13:49
Ameya Pore (University of Verona, Italy)
Nicola Piccinelli (University of Verona, Italy)
Giacomo De Rossi (University of Verona, Italy)
Matteo Piano (University of Verona, Italy)
Daniele Meli (University of Verona, Italy)
Diego Dall'Alba (University of Verona, Italy)
Riccardo Muradore (University of Verona, Italy)
Paolo Fiorini (University of Verona, Italy)
EndoVine: Soft Robotic Endoscope for Colonoscopy
PRESENTER: Ameya Pore
13:51
Jarrett Ten (University of Sheffield, UK)
Quentin Lahondes (University of Sheffield, UK)
Shuhei Miyashita (University of Sheffield, UK)
Dana Damian (University of Sheffield, UK)
Development and Control of a Robotic Simulator for Peristaltic Motion
PRESENTER: Quentin Lahondes
13:53
Alice Valeria Iordache (Politecnico di Milano, Italy)
Alessandro Casella (Politecnico di Milano, Istituto Italiano di Tecnologia, Italy)
Elisa Iovene (Politecnico di Milano, Italy)
Junling Fu (Politecnico di Milano, Italy)
Federico Pessina (Humanitas Research Hospital, Italy)
Marco Riva (Humanitas Research Hospital, Italy)
Giancarlo Ferrigno (Politecnico di Milano, Italy)
Leonardo Mattos (Istituto Italiano di Tecnologia, Italy)
Elena De Momi (Politecnico di Milano, Italy)
Envisioning Robotic Exoscope: Concept and Preliminary Results
PRESENTER: Elisa Iovene
13:55
Adam J Sperry (University of Utah, United States)
Jake J Abbott (University of Utah, United States)
Minimum-Parameter Adaptive Propulsion Matrix of Screw-Type Magnetic Capsule Endoscopes
PRESENTER: Adam J Sperry
13:57
Max B. Schäfer (University of Stuttgart, Institute of Medical Device Technology, Germany)
Julia Nawratil (University of Stuttgart, Institute of Medical Device Technology, Germany)
Moritz Hemmer (University of Stuttgart, Institute of Medical Device Technology, Germany)
Sophie Weiland (University of Stuttgart, Institute of Medical Device Technology, Germany)
Peter P. Pott (Institut für Medizingerätetechnik, Universität Stuttgart, Germany)
Cable-Driven Linear Haptic Display for Medical Interventions
PRESENTER: Max B. Schäfer
13:59
Lianne R. Johnson (Rice University, United States)
Michael D. Byrne (Rice University, United States)
Marcia K. O'Malley (Rice University, United States)
Comparison of Performance Metrics for Real-Time Haptic Feedback in Surgical Skill Training
14:01
Kiana Abolfathi (School of Computer Science and Electronic Engineering, University of Essex, UK)
Mohammad Reza Hairi Yazdi (School of Mechanical Engineering, University of Tehran, Iran)
Ali Kafash Hoshiar (School of Computer Science and Electronic Engineering, University of Essex, UK)
Predictable Therapeutic Microswarm Dispersion for Targeted Drug Delivery Application
PRESENTER: Kiana Abolfathi
14:03
Yash Chitalia (Boston Children's Hospital and Harvard University, United States)
Abdulhamit Donder (Boston Children's Hospital & Harvard Medical School, United States)
Pierre Dupont (Boston Children's Hospital and Harvard University, United States)
Modeling Telescoping Tendon-Actuated Continuum Robots
PRESENTER: Yash Chitalia
14:05
Ravi Naik (Imperial College London, UK)
Kaizhe Jin (Imperial College London, UK)
Alexandros Kogkas (Imperial College London, UK)
Hutan Ashrafian (Imperial College London, UK)
Ara Darzi (Imperial College London, UK)
George Mylonas (Imperial College London, UK)
Preliminary Findings of a Multimodal Sensor System for Measuring Surgeon Cognitive Workload
PRESENTER: Ravi Naik
14:07
Junhong Chen (Imperial College London, UK)
Zeyu Wang (Imperial College London, UK)
Ruiqi Zhu (King's College London, UK)
Ruiyang Zhang (Imperial College London, UK)
Weibang Bai (Imperial College London, UK)
Benny Lo (Imperial College London, UK)
Reinforcement Learning for Path Generation for Surgical Robot Maneuver
PRESENTER: Ruiyang Zhang
14:09
Hisham Iqbal (Imperial College London, UK)
Ferdinando Rodriguez Y Baena (Imperial College, UK)
Augmented Reality for Seamless Human Robot Interaction in Surgery
PRESENTER: Hisham Iqbal
14:11
Radian Gondokaryono (University of Toronto; PCIGITI Sickkids Hospital, Canada)
Mustafa Haiderbhai (University of Toronto; PCIGITI Sickkids Hospital, Canada)
Adnan Munawar (John Hopkins University, United States)
Thomas Looi (PCIGITI Sickkids Hospital, Canada)
James Drake (PCIGITI Sickkids Hospital, Canada)
Lueder Kahrs (University of Toronto; PCIGITI Sickkids Hospital, Canada)
A Modular ROS-Based dVRK Teleoperation Controller Architecture
14:13
Lingyu Lyu (Imperial College London, UK)
Elena Monfort-Sanchez (Imperial College London, UK)
Mark Runciman (Imperial College London, UK)
George Mylonas (Hamlyn Centre for Robotic Surgery, UK)
James Avery (Imperial College London, UK)
FMRI and MEG Compatible Hand Motion Sensor
PRESENTER: James Avery
14:15
Spyridon Souipas (Imperial College London, UK)
Stephen Laws (Imperial College London, UK)
Ferdinando Rodriguez Y Baena (Imperial College, UK)
Brian Davies (Imperial College London, UK)
Signature Robot: a Miniature Robot for Orthopaedic Surgery
PRESENTER: Stephen Laws
14:17
Margaret Rox (Vanderbilt University, United States)
Aidan Copinga (University of Utah, United States)
Robert Naftel (Vanderbilt University Medical Center, United States)
Robert Webster (Vanderbilt University, United States)
Alan Kuntz (University of Utah, United States)
Optimizing Continuum Robot Tendon Routing for Minimally Invasive Brain Surgery
PRESENTER: Margaret Rox
14:19
Sina Najjari (University of Leeds, UK)
Peter Culmer (University of Leeds, UK)
Ali Alazmani (University of Leeds, UK)
Design, Fabrication, and Evaluation of a Biomimetic Soft Peristaltic Pump for Biomedical Applications
PRESENTER: Sina Najjari
14:21
Lap Wing Cheung (Chinese University of Hong Kong, Hong Kong)
Ka Chun Lau (Chinese University of Hong Kong, Hong Kong)
Flora Leung (The Chinese University of Hong Kong, Hong Kong)
Donald Ngo Fung Ip (The Chinese University of Hong Kong, Hong Kong)
Henry Chow (The Chinese University of Hong Kong, Hong Kong)
Philip Wai Yan Chiu (The Chinese University of Hong Kong, Hong Kong)
Yeung Yam (The Chinese University of Hong Kong, Hong Kong)
Distal Joint Rotation Mechanism for Endoscopic Robot Manipulation
PRESENTER: Ka Chun Lau
14:30-15:30 Session 17: Industry Forum

Industry Panel:

  • Mr Jim Nevelos, Vice President of Advanced Technology and Research (Joint Replacement), Stryker Corp.
  • Mr Ori Hadomi, Vice President of Strategic Initiatives and Partnerships, Medtronic Inc.
  • Mr Brian Uthgenannt, Global Marketing Manager, Corin Group.
  • Mr Branko Jaramaz, Senior Director, Research and Development, Smith and Nephew
  • Mr Thomas Küenzi, Senior Director Velys R&D, DePuy Synthes
  • Mr Felix Wandel, Vice President of Robotics and Technology (EMEA), Zimmer Biomet
Chairs:
Ferdinando Rodriguez Y Baena (Imperial College)
Johann Henckel (Royal National Orthopaedic Hospital, UK)
Alister Hart (Royal National Orthopaedic Hospital & UCL, UK)
15:30-16:00Coffee Break
16:00-17:00 Session 18: Clinical Insights
Chairs:
Amir Szold (Assia Medical Group, Israel)
Duke Herrell (Vanderbilt University, United States)
16:00
Anna Di Laura (Royal National Orthopaedic Hospital & UCL, UK)
Johann Henckel (Royal National Orthopaedic Hospital, UK)
Martin Belzunce (Royal National Orthopaedic Hospital, UK)
Harry Hothi (Royal National Orthopaedic Hospital & UCL, UK)
Alister Hart (Royal National Orthopaedic Hospital & UCL, UK)
3D Printed Cups for Acetabular Reconstruction: a 3D-CT Implant Study
PRESENTER: Anna Di Laura
16:12
Christophe Chautems (ETH Zurich, Switzerland)
Nikola Cesarovic (ETH Zurich, Switzerland)
Peter Bode (University of Zurich, Switzerland)
Bradley Nelson (ETH Zurich, Switzerland)
Firat Duru (University Heart Center Zurich, Switzerland)
Results of in Vivo Cardiac Arrhythmia Ablations with an Electro-Magnetic Navigation System
16:24
Tom Pampiglione (University College London Hospital, UK)
Lluis Fumado (Hospital Del Mar, Spain)
Maarten Ruben Grootendorst (Lightpoint Medical Ltd., Netherlands)
Kunal Vyas (Lightpoint Medical Ltd., UK)
Manish Chand (University College London Hospital, UK)
A Drop-in Robotic Gamma Probe for Minimally Invasive Radioguided Surgery
PRESENTER: Tom Pampiglione
16:36
Richard Hendrick (Virtuoso Surgical, Inc., United States)
Neal Dillon (Virtuoso Surgical, Inc., United States)
Lauren Branscombe (Virtuoso Surgical, Inc., United States)
Trevor Bruns (Virtuoso Surgical, Inc., United States)
Evan Blum (Virtuoso Surgical, Inc., United States)
Moffat Oresi (Virtuoso Surgical, Inc., United States)
Stephanie Amack (Virtuoso Surgical, Inc., United States)
S. Duke Herrell III (Vanderbilt University Medical Center, United States)
Robert Webster III (Vanderbilt University, United States)
The Virtuoso Surgical System: First Live Animal Experience
16:48
Brendan F. Judy (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
A. Daniel Davidar (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Andrew Hersh (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Carly Weber-Levine (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Amanda N. Sacino (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Brian Y. Hwang (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Tej D. Azad (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Ann Liu (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Joshua Materi (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Tara Dedrickson (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
William S. Anderson (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Nicholas Theodore (Johns Hopkins Hospital, Baltimore, Maryland, USA, United States)
Neurosurgical Robotics: Pushing the Boundaries with a Single Platform for the Sacrum to the Cranium
PRESENTER: Brendan F. Judy
17:00-17:45 Session 19: Karl Storz - Harold Hopkins Golden Telescope Lecture: Prof Alex Golby, "Optimizing surgery for patients with brain tumors: The right information at the right time in the right place"

Professor of Neurosurgery and Professor of Radiology, Harvard Medical School 

Abstract: Treating patients with brain tumors requires balancing the need for aggressive oncologic therapy with preservation of neurologic function. Treatment for nearly all brain tumor patients starts with surgical resection of the lesion. Maximal removal of tumor tissue–if it can be accomplished without causing additional neurologic deficit–provides the best prognosis and sets the stage for efficacious adjuvant treatment. Achieving maximal safe surgical resection however can be challenging. In order to perform optimal surgery, the surgeon must have a patient specific understanding of the location and extent of the tumor as well as of adjacent and at-risk eloquent structures in the brain. Multimodal imaging now allows the delineation of individual functional anatomy including cortical (grey matter) and subcortical (white matter) eloquent areas as well as the relationship to the tumor. Bringing this data into the operating room and coordinating it with the surgical gesture is critical to make it most informative for guiding surgical decision making. As the surgery progresses, brain shift changes the configuration of these critical anatomic relationships and efforts to measure brain shift, tissue resection, and other intraoperative changes are essential to maintain the accuracy of mapping. At the completion of surgery, creating and exporting a data file which includes surgical observations, locations of tissue samples and other critical information from the surgery can best inform post-operative adjuvant therapy including novel strategies to deliver agents directly to the tumor.

Biography: My research focuses on the translation of a broad range of neuroimaging techniques to neurosurgical planning and intraoperative guidance. The overarching goal of this work is to help surgeons perform optimal brain surgery by defining and visualizing critical brain structures and pathologic tissue to be removed.

Since 1998, I have worked on the development and validation of fMRI for the pre-operative evaluation of patients with lesions in and near critical areas of the brain. This has been a translational research effort which adapted fMRI, initially developed as a neuroscience technique to be applied in groups of subjects to make statistical inferences about populations, to the vastly different scenario of clinical decision-making for individual patients. Since our research program began at BWH in 2003, we have developed new techniques for the use of fMRI in single subject analyses necessary for surgical planning. In addition, we have developed numerous acquisition strategies geared towards accommodating the limited neurologic functions of some patients as well as analytic approaches to maximize the utility of fMRI for surgical planning. Presurgical fMRI has the potential to bring meaningful pre-operative individualized functional anatomy mapping to neurosurgeons around the world as an alternative to awake mapping, a technique which is demanding and remains limited to very specialized centers.

I have also worked extensively on the translation of diffusion MRI (dMRI) including tensor imaging (DTI) to map white matter anatomy in neurosurgical patients. Diffusion MRI allows the in vivo depiction of the location, course and integrity of macroscopic white matter tracts in the brain through a process known as tractography. As with fMRI, the translation of this technology to clinical decision-making has required numerous fundamentally novel approaches. We have developed segmentation approaches for defining tracts based on high dimensional clustering as well as statistical atlases which allow labeling of individual patient tracts even in the setting of mass effect and peritumoral edema. My group works collaboratively with MRI physics and MRI analysis groups to continue to be at the forefront of technical innovation. We have released many of our tools to the public via 3D Slicer (slicer.org) and we have organized several international challenge workshops to apply diffusion techniques to real world clinical data.

With both these methods, translation of the technology required understanding of clinical needs, constraints, and opportunities for improved clinical care. Specific analysis techniques needed to be developed to adopt these techniques so that they were applicable to single subject data, and, in particular, to neurologic patients who have structural lesions and often are limited by their neurological deficits. In these efforts, we work closely and collaboratively with scientists in radiology and computer science to translate emerging technical innovations into the operating room.

Another major area of translational investigation is in the development of intraoperative imaging techniques. I was the lead surgeon in developing the AMIGO (Advanced Multi-modality Image-Guided Operating Suite) at BWH and serve as the Co-director of AMIGO. AMIGO is one of the key resources of the National Center for Image Guided Therapy funded by NIH. This suite contains all contemporary imaging methods within an operating room environment and was specifically designed to support translational research. The suite is the site of many of surgical procedures in which we are developing strategies for intraoperative imaging and guidance.

Several of our important research efforts are built on the AMIGO platform. These include the intra-operative use of high field MRI including development of intra-operative dMRI tractography. We have also leveraged the resources of the AMIGO suite to develop novel strategies to simplify intraoperative imaging using techniques such as ultrasound and stereovision to give surgeons information in near real time to guide surgery. Another area of research leveraging the resources of AMIGO is the development of tissue level molecular imaging.We have funded collaborative projects using mass spectrometry, Raman spectroscopy, and fluorescence imaging.Our eventual goal is to give surgeons in most settings tools that will help them to perform safer and more effective surgery.

Chair:
Ferdinando Rodriguez Y Baena (Imperial College)
17:45-18:00 Session 20: Awards & Closing Ceremony

Poster Awards Chair: Elena De Momi (Politecnico di Milano, Italy)

Podium Awards Chair: Daniel Elson (Imperial College London, UK)

Chair:
Ferdinando Rodriguez Y Baena (Imperial College)