In Vitro Navigation of a Magnetic Sphere Using a Model Predictive Controller for Neurovascular Targeted Drug Delivery Applications

Title:In Vitro Navigation of a Magnetic Sphere Using a Model Predictive Controller for Neurovascular Targeted Drug Delivery Applications

Authors:Derick Sivakumaran, Fabian Christopher Landers, Quentin Boehler, Christophe Chautems, Salvador Pané and Bradley J. Nelson

Conference:HSMR2022

Tags:Model Predictive Control, Neurovascular interventions, Remote Magnetic Navigation and Targeted drug delivery

Abstract:

In this work, we focused on magnetic navigation inside a two-dimensional (2D) model of the main vasculature of the human brain (namely the circle of Willis). We manipulated a small-scaled untethered magnetic sphere inside an electromagnetic navigation system (eMNS), consisting of eight electromagnets to show remote magnetic navigation.