VPH2018: VIRTUAL PHYSIOLOGICAL HUMAN 2018
PROGRAM

Days: Wednesday, September 5th Thursday, September 6th Friday, September 7th

Wednesday, September 5th

View this program: with abstractssession overviewtalk overview

08:30-09:00 Session 1: Opening Ceremony

The confirmed chairs for these sessions are:

-José Antonio Mayoral, Dean of the University of Zaragoza.

-Liesbet Geris, Director of VPH Institute.

-José Ángel Castellanos, Director of the EINA.

-Ignacio Garcés, Director of I3A.

-Pilar Alegría, Goverment of Aragón

10:00-10:30Coffee Break
10:30-12:30 Session 3A: Cardiovascular modeling: from simulation to clinical outcome organised by E-cardiology I
10:30
Phase maps based on the electrograms from basket catheters might generate false rotors (abstract)
10:45
Tx, a new biomarker for in-silico early assessment of drug-induced proarrhythmic risk (abstract)
11:00
Left Atrium Patient-Specific Modelling from Electroanatomical Maps (abstract)
11:15
Clinical MRI-based multiscale computational models of heart and torso to investigate the role of anatomy on ECG (abstract)
11:30
A Bayesian Filtering methodology to identify key drivers of ventricular repolarization variability (abstract)
11:45
Automatic Atrial Fibrillation Initiation for the Evaluation of Proarrhythmic Risk at Tissue In-Silico Models (abstract)
12:00
Arrhythmogenic mechanisms in silent acute myocardial ischemia (abstract)
12:15
Neural networks to classify ischemic ECG signals: a computational study (abstract)
10:30-12:30 Session 3B: Surgical Decision Support
Location: Room 0.01
10:30
Surgical Decision Support in Knee Surgery (abstract)
11:00
Mathematical model of fluid status after intravenous fluid infusion (abstract)
11:15
Automation and validation of a musculoskeletal model setup for predicting TKA functional outcome (abstract)
11:30
Towards Real-Time Transaortic Pressure Gradient Computation (abstract)
11:45
Computerized Clinical Decision Support System for Childbirth Management: Preliminary Considerations (abstract)
12:00
Surgical planning in relation to atrioventricular valve regurgitation in single-ventricle physiology: the dilemma of valve repair (abstract)
10:30-12:30 Session 3C: Clinical Applications and Personalized Medicine: Models in Oncology
Location: Room 0.02
10:30
In Silico Oncology: Building and validating hypermodels and Oncosimulators as clinical decision support systems in the framework of the EU-US CHIC project (abstract)
11:00
Assessing Radiotherapy Effectiveness in Prostate Cancer: model validation on the EUREKA2 cohorts (abstract)
11:15
In Silico Oncology: A vascular tumour growth based Oncosimulator for reproducing the clinical time-course of breast cancer patients undergoing bevacizumab mono-therapy (abstract)
11:30
Bridging the gap between basic science and clinical oncology by IT infrastructures for models to support clinical decision support (abstract)
11:45
Tackling acquired resistance mechanisms in malignant melanoma. (abstract)
12:00
In Silico Evaluation of Inhibitory Potential with Rapid and Reliable Binding Affinity Predictions (abstract)
12:15
Progress in cell-based, quasi-lattice-free simulations of vascularized solid tumours (abstract)
10:30-12:30 Session 3D: Multiscale modeling I
Location: Room 0.03
10:30
Multiscale VPH models: better predictive accuracy or increased explanatory power? Reflection on the hip fractures problem (abstract)
11:00
Physiome: encouraging reproducibly FAIR computational modelling (abstract)
11:15
The Role of Multiscale Time in Multiscale Systems Biology (abstract)
11:30
Efficacy of hip fracture risk reduction using multifactorial interventions combining environmental hazard management and balance training (abstract)
11:45
Forward simulations of three-dimensional, continuum-mechanical musculoskeletal system models (abstract)
12:00
In-Silico Modelling of Oesophageal Tissue for Treatment of Long Gap Oesophageal Atresia (abstract)
12:15
Multiphysic Approach for Bicomponent Tissue Engineered Bone Grafts (abstract)
10:30-12:30 Session 3E: Inverse problems for model personalization I
Location: Room 0.04
10:30
The Effect of Kinematic and Dynamic Redundancy on the Assessment of Joint Reaction Loads (abstract)
10:45
Personalization of one-dimensional blood flow models via a reduced-order unscented Kalman filter in the frequency domain (abstract)
11:00
Overcoming aliasing in velocity-encoded MRI for blood flow computations (abstract)
11:15
Modelling of impulsive source in a prestressed soft tissue (abstract)
11:30
Clinical Personalization of Models of Left Ventricular Electromechanics (abstract)
11:45
Modeling and inverse problems in tumor growth (abstract)
12:00
Combined Machine Learning and Textural Image Analysis of endometrial Ultrasound images for prediction of egg implantation rate and ongoing pregnancy in infertile patients (abstract)
12:15
Mathematical modelling acute myocardial infarction using in vivo magnetic resonance imaging (abstract)
10:30-12:30 Session 3F: Industry Session: MATERIALISE

Hands-on-cardiovascular image analysis workshop - MATERIALISE

Location: Room 1.03
12:30-14:00Lunch Break
14:00-15:30 Session 5A: Cardiovascular modeling: from simulation to clinical outcome organised by E-cardiology II
14:00
Image-derived, population specific analysis of the mitral valve apparatus: towards a realistic setting for device in-silico testing (abstract)
14:15
Uncertainty in Non-Invasive, Numerical Assessment of Pressure Drop across a Coarctation of the Aorta (abstract)
14:30
Inaccuracies of clinical pressure gradient measurements: Quantification of pressure recovery in aortic valve conditions (abstract)
14:45
Predictive Modeling of Isolated Aortic Valve Replacement (abstract)
15:00
A Clinical Pathway for Patient-Specific Simulation of Left Ventricle Hemodynamics Based on Echocardiography (abstract)
15:15
Effect of Central versus Peripheral ECMO Support on Blood Flow Distribution: A Computational Study (abstract)
14:00-15:30 Session 5B: Orthopaedics and craneofacial I
Location: Room 0.01
14:00
Surrogate-based optimization of acetabular implant design through minimization of stress shielding (abstract)
14:15
Twente Spine Model: A Study of the Intervertebral Disc Forces in Flexion (abstract)
14:30
Patient-specific musculoskeletal models to characterise the response to disease activity in patients with Juvenile Idiopathic Arthritis (abstract)
14:45
Estimation of Subject-specific Knee Ligament Properties (abstract)
15:00
A Collaborative Strategy to Establish Reproducibility in Simulation-Based Prediction of Natural Knee Mechanics (abstract)
15:15
Investigating bone health in trans-femoral amputees (abstract)
14:00-15:30 Session 5C: Agent-based models
Location: Room 0.02
14:00
Multiscale Biophysical Modeling of Receptor Activation, Signaling and Trafficking in Cancer (abstract)
14:15
Lattice-gas cellular automaton models for collective cell migration (abstract)
14:30
Insights of avascular tumour growth by means of a biphasic porous elastic model (abstract)
14:45
In vitro and in silico characterization of computational prediction of cement infiltration in osteoporotic bones: an in vitro and in silico biomechanical study (abstract)
15:00
Statistical Shape Analysis of the Right Ventricular Outflow Tract in Patients with Tetralogy of Fallot (abstract)
15:15
3D Agent Based Modelling of Intervertebral Disc Nucleus Pulposus cells to simulate the effects of disc tissue property alterations (abstract)
14:00-15:30 Session 5D: Multiscale modeling II
Location: Room 0.03
14:00
Computational modelling of the effect of growth factors on human mesenchymal stem cell proliferation in 3D porous scaffolds (abstract)
14:15
Insights into mechanisms of resistance to renal denervation using topological analysis of simulation (abstract)
14:30
Computational Modelling of the Role of GLUT2 in Glucose Uptake by Intestinal Epithelial Cells (abstract)
14:45
OpenCOR: a modelling environment for reproducible science (abstract)
15:00
Computational Model of Wound Healing Angiogenesis: a Preliminary Study (abstract)
14:00-15:30 Session 5E: Inverse problems for model personalization II
Location: Room 0.04
14:00
Effective estimation for biomedical models (abstract)
14:30
Numerical design of composite biomarkers (abstract)
14:45
Validation of a sequential data assimilation method applied to cardiac electrophysiology (abstract)
15:00
Reduced Order Modeling for Uncertainty Quantification of the cardiac function (abstract)
15:30-16:00 Session 6A: Flash Presentation I
15:30
Patient Profiles and Clinical Event Simulations in a Left Heart Simulator (abstract)
15:34
Steps, energy expenditure and heart rate agreement of five activity trackers (abstract)
15:38
Soft Tissue Growth and Remodelling Framework: Application in Myocardial Infarction (abstract)
15:42
Evaluation of SPH method for cardiac flow simulations (abstract)
15:46
In vivo evaluation of noradrenaline effects using a heart model (abstract)
15:50
Non-invasive cardiac stress tests: a 0D modelling approach (abstract)
15:54
Modular open-source workflow for in silico studies of atrial electrophysiology (abstract)
15:30-16:00 Session 6B: Flash Presentation II
Location: Room 0.01
15:30
Simulation approach for the prediction of hemodynamic after virtual mitral valve repair interventions (abstract)
15:34
Patient specific 0D model of the systemic circulation to simulate the effects of valve stenosis and regurgitation (abstract)
15:38
Fluid parametric model of the blood flow in the ascending aorta (abstract)
15:42
Numerical study of thrombus formation processes in branched vascular networks (abstract)
15:46
The impact of genomics in the development of a diagnostic model for stable coronary artery disease. (abstract)
15:50
On modelling patient-specific carotid atherosclerotic plaque formation (abstract)
15:54
An integrated image-based framework for the mechanical characterization of patient-specific blood vessels (abstract)
15:30-16:00 Session 6C: Flash Presentation III
Location: Room 0.02
15:30
Atrial Flutter Re-entrant Circuit Identification based on Body Surface Phase Mapping (abstract)
15:34
Development of a Finite Element Model to assess tumour tissue evolution (abstract)
15:38
Outlet resistance estimation for 1D pulse wave propagation modelling in the cerebral arteries (abstract)
15:42
Agent-based modelling of contraction of burns (abstract)
15:46
The Back-UP Project: Towards predictive diagnosis and personalised medicine for NLBP underpinned by the VPH technologies and vision (abstract)
15:50
Security Tools for Modern Computational Medicine (abstract)
15:54
A Rubric for Evaluating the Credible Practice of Computational Modeling and Simulation in Healthcare (abstract)
15:30-16:00 Session 6D: Flash Presentation IV
Location: Room 0.03
15:30
Application of a genetic algorithm to check the variation of the biomechanical properties of asymptomatic and incontinent women (abstract)
15:34
Morphing detailed human body models to represent weight change (abstract)
15:38
Electromagnetic stimulation chambers for chondrocytes (abstract)
15:42
Coupling of finite element and electro-chemical models of the uterine muscle (abstract)
15:46
Numerical simulation of intraocular lens implantation in the lens capsule during the cataract surgery procedure (abstract)
15:50
Global sensitivity analysis of HD-sEMG amplitude descriptors from a cylindrical multilayered muscle model (abstract)
15:54
Three-dimensional (3D) Multiscale Model of the Contracting Ventricle (abstract)
15:30-16:00 Session 6E: Flash Presentation V
Location: Room 0.04
15:30
Virtual Assessment of the Primary Stability of Hip Prostheses (abstract)
15:34
Augmentation and Screw Assisted Internal Fixation (SAIF) in osteoporotic vertebrae: a finite element analysis of a new technique (abstract)
15:38
Model-based design of 3D-printed calcium-phosphate based biomaterials for dental applications (abstract)
15:42
An Agent-Based Model of the Bone Remodelling Process and its Disruption by Multiple Myeloma (abstract)
15:46
Patient-specific frequency analysis for the preoperative evaluation of implant stability (abstract)
15:50
Biomechanical Behaviour Of The Joint Sub/Astragalin, Skills with Supported Bodies, with a View to Designing a Prosthetic Replacement Prototype for Talus. (abstract)
15:54
Optimizing material and design specifications of bioresorbable CMF plates using an in-silico model of a 4-point bending test (abstract)
16:00-16:30Coffee Break
16:30-18:00 Session 7A: In silico Medicine in FP9

Liesbet Geris – VPHi Executive Director: “The VPH Institute: promoting in silico medicine research” and “the VPHi FP9 Position Paper”

Violeta Isabel Pérez Nueno - European Commission Officer: “Future priorities of in-silico medicine”

Tina Morrison (FDA): "FDA research priorities for in silico medicine"

 Q&A

16:30-18:00 Session 7B: ERC & MSCA session

ATTRACTIVE OPPORTUNITIES FOR YOUNG RESEARCHERS IN EUROPEAN PROJECTS (H2020)

This talk will show an overview of different opportunities for young researchers in the frame of European Projects (H2020).

In order to cover all the aspects involved in a proposal preparation, both the formal issues of the calls as well as success cases will be presented.

Fundamental elements regarding preparation of the proposal will be reviewed, with particular emphasis on the definition of the problem that wants to be solved, its significance and the selection of an innovative methodology to tackle it.

Based on previous experiences of H2020 applicants, tips will be provided on: the importance of identifying the best moment to present the proposal; the time you should reserve to not only write but more crucially to think about your idea; or the benefit of seeking for advice from colleagues with expertise in different disciplines, not necessarily close to yours.

Finally, the talk will go over the way you report your CV and your past achievements and how this can influence how others may or may not see you as the best possible researcher to carry out the project you are presenting.

Location: Room 0.01
18:00-20:30 Session 8: VPH networking event (only registration for VPH members)

18:05 – 18:15: Lies Geris – VPHi Executive Director: “Introduction on the scope of the session”

18:15 – 18:25: Martina Contin – VPHi Manager ”VPHi as a project partner: community engagement and outreach”

18:25– 19:00: Juan Riese – Spanish NCP: “Presentation of the VPH related calls in last work program of H2020”

19:00: – 19:30: Q&A session on H2020 calls

19:30 – 20:30: Networking session – Drinks and small buffet

 

21:00-22:30Student's social night
Thursday, September 6th

View this program: with abstractssession overviewtalk overview

09:00-10:00 Session 9: Plenary speaker II
09:00
Human In Silico Drug Trials with Multiscale Models of the Heart (abstract)
10:00-10:30Coffee Break
10:30-12:30 Session 10A: Cardiovascular modeling: from simulation to clinical outcome organised by E-cardiology III
10:30
Cardiac dynamics and arrhythmic risk in aged and failing hearts: insights from experimental and computational research (abstract)
11:00
Combining tissue heterogeneity and anisotropy in a fractional model of cardiac electrophysiology (abstract)
11:15
A patient-specific fluid-structure interaction analysis of TAVI procedure (abstract)
11:30
Effect of fibrosis on BSPM of patients with focal atrial tachycardia (abstract)
11:45
Validation of a reduced order model for prediction of FFR, using in vivo data, 3D INS and UQ & SA (abstract)
12:00
Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat repolarization variability under sympathetic provocation (abstract)
12:15
Computational pre-surgical planning of cardiovascular patch reconstruction – pre-operative structural and hemodynamic performance in selected clinical cases (abstract)
10:30-12:30 Session 10B: Orthopaedics and craneofacial II
Location: Room 0.01
10:30
Towards functional pre-planning in orthopaedic surgery (abstract)
11:00
Stability of anterograde intramedullary nails in distal femoral fractures (abstract)
11:15
Apex Vertebra Transpositions in the 3D Optical Diagnosis of 372 Patients with Adolescent Idiopathic Scoliosis (abstract)
11:30
A phantom-less calibration technique for use in femur strength prediction (abstract)
11:45
Design of an electro-stimulating system for a defective minipig mandible (abstract)
12:00
Integration of Cortical Thickness data in a Statistical Shape Model of the Scapula (abstract)
12:15
Development of a physiologically relevant structural model of the pelvic construct to simulate fracture (abstract)
10:30-12:30 Session 10C: Other applications in organ physiology
Location: Room 0.02
10:30
FE modelling of alveolar mechanics based on the Weaire-Phelan unit cell (abstract)
10:45
Modelling the cerebral diffusive spread of pathology in Parkinson’s disease (abstract)
11:00
An Averaged Geometry of the Human Nasal Cavity (abstract)
11:15
NEUROMAN: Implementing Neuro-Functionalized Computational Human Body Models (abstract)
11:30
How Ionic Imbalances Alter Axonal Conduction. A Computational Study. (abstract)
11:45
An in silico HBV model predicts viral response to the oral non-steroidal carboxylic acid FXR agonist EYP001a (abstract)
12:00
A preliminary in silico model of the thrombectomy procedure (abstract)
12:15
Customized design of colonic stents based on a parametric model (abstract)
10:30-12:30 Session 10D: Multiscale modeling III
Location: Room 0.03
10:30
A microstructurally-based material model for the description of skeletal muscle tissue (abstract)
10:45
Simulating Electromyography (EMG) Signals by Using a Generalized Bidomain Approach (abstract)
11:00
Semantics-based model discovery for renal transport (abstract)
11:15
Whole Brain Simulations in Mouse Elucidate Mechanisms of Local Cerebral Blood Flow Control (abstract)
11:30
Intracranial Aneurysms: A Patient-Specific Fluid-Solid-Growth (FSG) Framework with Modelling of Endothelial Response (abstract)
11:45
BioGears: An In-Silico Whole-Body Framework to Simulate Kinetics and Dynamics of Pharmaceuticals and Associated Reversal Agents (abstract)
12:00
Multiscale model of transport and uncoiling of ultralarge proteins in cellular blood flows (abstract)
10:30-12:30 Session 10E: Model Reduction, Big Data and Dynamic Data-Driven Systems I
Location: Room 0.04
10:30
Organs Hybrid Twin: towards a new paradigm in computational surgery (abstract)
11:00
On the evaluation of hip fracture risk using advanced machine learning techniques (abstract)
11:15
Deformable Augmented Reality via Model Order Reduction Methods (abstract)
11:30
A Model Execution Environment for Valvular Heart Condition Simulations (abstract)
11:45
Modelling and control of an adaptive biohybrid device for modulation of inflammation (abstract)
12:30-14:00Lunch Break
14:00-16:00 Session 12A: Cardiovascular modeling: from simulation to clinical outcome organised by E-cardiology IV
14:00
InSilc: In Silico Trials for drug-eluting bioabsorbable vascular scaffold (BVS) development and evaluation (abstract)
14:15
A platform for patient-specific vascular medicine: a case study of a chronic type-B aortic dissection (abstract)
14:30
In silico stent deployment in the coronary artery with plaque progression (abstract)
14:45
Embedded Computational Fluid Dynamics to study cardiovascular pathologies: Aortic Dissection. (abstract)
15:00
An anatomical surrogate of wall compliance in the child heart (abstract)
15:15
A rule based method for assigning fiber information to heart complex structures (abstract)
15:30
A 4D Flow MRI-based modelling approach to assess left ventricular function during rest and stress conditions (abstract)
15:45
Automatic segmentation of the atrial region using a competitive deformable model approach (abstract)
14:00-16:00 Session 12B: Impact and Injury
Location: Room 0.01
14:00
Effect of high-impact exercise on trabecular bone adaptation in postmenopausal women (abstract)
14:15
Patient-Specific Principal Component Analysis Stratifies Multiple Organ Dysfunction Outcomes based on Type 17 Immune Responses in Blunt Trauma Patients in the First 24 Hours Following Injury (abstract)
14:30
Thoracic Deformation in Nearside Oblique Sled Impacts (abstract)
14:45
Development and Evaluation of a Subject-Specific Brain Injury Model (abstract)
15:00
Effect of Bone Micromorphology on Multiple Crack Propagation: Finite-element Analysis (abstract)
15:15
DXA-based 3D patient-specific femur model simulations for hip fracture prediction (abstract)
15:30
Influence of the head size in the injury metrics for oblique impacts (abstract)
15:45
Using digital image correlation to validate meniscus tear patterns predicted by continuum damage models (abstract)
14:00-16:00 Session 12C: Image-based in-vitro analysis
Location: Room 0.02
14:00
Image-based in vitro analysis and computational modelling to characterise the mechanical environment of bone cells during osteoporosis (abstract)
14:30
A model for endothelial cell migration under flow conditions (abstract)
14:45
Calibrating a stochastic model of cell migration using image-based in vitro analysis and Bayesian optimization. (abstract)
15:00
Cerebral aneurysm tissue investigation: experiment and simulations (abstract)
15:15
IMAGO: an online platform for microscopy image analysis in in-vitro experiments (abstract)
15:30
On the context of use of directly validated spinal functional units FE models (abstract)
15:45
A novel 3D printed bioinspired cardiac pneumatic pump: from design to numerical and experimental study (abstract)
14:00-16:00 Session 12D: Multiphysics modeling I
Location: Room 0.03
14:00
In silico characterisation of the spatiotemporal evolution of stem cell niches during neotissue growth in 3D scaffolds during perfusion bioreactor culture (abstract)
14:30
Finite element analysis of individual cell migration under conditions of mechanical confinement (abstract)
14:45
Influence of the mechanical properties of cell nucleus on overall deformation of the cell: a computational study (abstract)
15:00
Cell resolved simulations of saccular aneurysms: effects of pulsatility and aspect ratio (abstract)
15:15
A multiphysic simulation of mechanotransduction effect through stretch operated channels in the uterine muscle. (abstract)
15:30
Modelling high shear-rate platelet aggregation on cellular level (abstract)
15:45
o2S2PARC – The Simulation Core of the NIH SPARC Initiative (abstract)
14:00-16:00 Session 12E: Model Reduction, Big Data and Dynamic Data-Driven Systems II
Location: Room 0.04
14:00
Development of Computational Patient Avatars by Manifold Learning (abstract)
14:15
The use of neuronal networks to help in pathologies diagnosis (abstract)
14:30
Full-blown 3D blood flow simulation in approach of effective compressibility as a model of vessel elasticity (abstract)
14:45
Reduced order modelling of electroporation in biological tissues for pulse delivery optimization (abstract)
15:00
Instabilities in Time Series from Intensive Care Units: A Sepsis Case Study (abstract)
14:00-16:00 Session 12F: Industry Session: Insilico Trials

Technology transfer and access: challenges and opportunities

In the last decades, universities and research centers have been applying modeling and simulation (M&S) to problems involving health and medicine, coining the new expression in silico clinical trials, but its use is still limited to a restricted pool of expert adopters.

Making M&S available to a broad spectrum of potential users (medical device and pharmaceutical companies, hospitals, healthcare institutions) would require an easy and controlled access to models and computational resources in a secure and compliant environment while protecting the intellectual property of the models’ creators.

Meanwhile, the European and USA regulatory agencies are starting to recognize the use of M&S in the research and technological development and to provide evidence in the approval process for new medical products. A joint effort from academia, industry and regulatory bodies is then required to reach a rapid adoption of a harmonized approach.

In this session, we will talk about potentials, limitations, challenges, and opportunities that the community has to deal with to leverage the significant value of M&S solutions which are being developed but are not fully exploited, in order to reach a broad adoption and democratization of simulations in healthcare.

Session topics:

  • Is there a “Valley of Death” for in silico medicine technologies? - Marco Viceconti, Executive Director at Insigneo Institute for in silico Medicine.
  • In silico modelling: From lab to the end-users - Javier Saiz, Professor at Universidad Politécnica de Valencia.
  • Learning from other industries: exploiting world class research to accelerate industrial innovations - Thierry Marchal, ANSYS Global Industry director.
  • One model for all and all efforts as one! - Nico Verdonschot, Scientific Director of Technical Medical Institute at University of Twente.
  • Technology transfer and technology access. How InSilicoTrials is working with researchers and industry – Luca Emili, CEO at InSilicoTrials Technologies.
16:00-16:30Coffee Break
16:30-19:00 Session 13: In silico clinical trials – a disruptive innovation for biomedical industry

Target: Industry specialists (product developers, regulatory affair, clinical trialists, etc.)

Tentative programme

16:30 – 16:45  The emerging regulatory landscape for in silico methods – Tina Morrison, FDA

16:45 – 17:30  Tools and services for in silico clinical trials: Moderator: Thierry Marchal, Avicenna Alliance.

                        Ansys – Representative.

                        Materialise – Sjoerd Kolk.

                        InsilicoTrials – Luca Emili.

                        Quibim – Angel Alberich-Bayarri.

17:30 – 17:45  In silico Clinical Trials: A vision of the future: Marco Viceconti, Insigneo Institute

17:45 – 18:00  Examples of early applications: Mark Palmer, Medtronic

18:00 – 18:10  Scalability of Computational Medicine applications: Peter Coveney, CompBioMed CoE

18:10 – 18:45  Round table. Moderator: Thierry Marchal, Avicenna Alliance

 

20:30-22:30Social Dinner
Friday, September 7th

View this program: with abstractssession overviewtalk overview

09:00-10:00 Session 14: Plenary speaker III
09:00
Cell Shape Information: Retrieval and Physiological Consequences (abstract)
10:00-10:30Coffee Break
10:30-12:30 Session 15A: Signalling networks
10:30
Mathematical modelling of cancer signalling dynamics, drug responses and prognosis (abstract)
11:00
Differential HMGB1 Network Connectivity may underlie the Protective Effect of N-acetylcysteine in the Context of Acetaminophen Toxicity in Pediatric Acute Liver Failure (abstract)
11:15
Understanding the interactions between Wnt and BMP signalling pathways in human Periosteum Derived Cells (abstract)
11:30
Reverse Engineering Methods to Study Osteochondral Regulatory Networks – a tool to identify potential drug targets (abstract)
11:45
Modeling Multistep Molecular Communication Events in the Axonal Neuron Microtubule Network in Amyloid Beta Neurodegeneration (abstract)
10:30-12:30 Session 15B: Image-based in-vivo analysis
Location: Room 0.01
10:30
Tissues, Information and Computers: Image-driven modelling of limb development (abstract)
11:00
Validation of a reconstruction method of femoral artery models from computed tomography and application to in vivo cases (abstract)
11:15
Validation of a 3D in-stent restenosis model using μCT and histology data (abstract)
11:30
Image Segmentation and Mesh Generation for Biomedical Applications (abstract)
11:45
Parametric Anatomical Models for Cardiovascular Device Evaluation (abstract)
12:00
Experimental validation of finite element analysis of a composite clavicle using digital image correlation (abstract)
12:15
An in silico model of human liver regeneration to predict critical factors controlling the recovery phenotype (abstract)
10:30-12:30 Session 15C: Multiphysics modeling II
Chairs:
Location: Room 0.03
10:30
Elucidating the importance of drug dissolution and specific-binding in a 2D model of arterial drug-eluting stents (abstract)
10:45
Multiphysics approach of confined cell migration (abstract)
11:00
A Mathematical Model of Cerebral Vasospasm and Comparison between Treatment Strategies (abstract)
11:15
Structured fractal tree model for flow simulation in coronary vascular tree (abstract)
11:30
Predicting cardiac toxicity of drugs using the Living Heart Model (abstract)
11:45
A fluid-electro-mechanical model of the human heart for supercomputers (abstract)
12:00
Multiphysics modelling of damage-induced response in arterial tissues: a chemo-mechano-biological computational framework for in-stent restenosis (abstract)
12:15
In Silico Investigation of Thrombosis Initiation in Left Ventricular Assist Device (abstract)
10:30-12:30 Session 15D: Mechanical cues in health and disease mechanisms organized by European Society of Biomechanics (ESB)
Location: Room 0.02
10:30
Biomechanical Analysis of the Pedicle Screws and Cement Injection Influence in the Sacral Region Stiffness - A Finite Element Analysis (abstract)
10:45
A computational investigation of the link between wall shear stress after stent deployment in coronary arteries and neo-intimal coverage. (abstract)
11:00
Simulating cartilage endplate early degradation to understand intervertebral disc degeneration (abstract)
11:15
Combined in-vitro/in-silico model of biodegradation (abstract)
11:30
Estimation of Diabetic Retinal Micronaneurysm Perfusion Parameters Based on Computational Fluid Dynamics Analysis (abstract)
11:45
Impact of the TAR technique for ventral hernia repairs on the abdominal wall biomechanics: a numerical study. (abstract)
12:00
Investigating mechanisms of response to AV fistula for the treatment of hypertension using a mathematical model of physiology (abstract)
10:30-12:30 Session 15E: Industry Session
Location: Room 0.04
10:30
Modeling Approach to Determine Optimal Prediabetic Diet (abstract)
10:50
A Mock Submission to Initiate a Clinical Trial in the U.S. (abstract)
11:10
Applying body-composition models in drug discovery (abstract)
11:30
New Opportunities for Computational Biomechanics In the Industry (abstract)
12:30-14:00Lunch Break