Physiological Effects and Patient Comfort: High-Flow Nasal Oxygen Therapy in Neonates with Respiratory Distress Syndrome

EasyChair Preprint no. 13689

Abstract

High-flow nasal oxygen (HFNO) therapy has emerged as a significant intervention for managing respiratory distress syndrome (RDS) in neonates, offering an alternative to more invasive ventilation methods. This abstract  reviews the physiological effects and patient comfort associated with HFNO therapy in this vulnerable population. HFNO delivers heated and humidified oxygen at flow rates exceeding the patient's inspiratory demand, thereby reducing work of breathing and improving gas exchange. Clinical studies have demonstrated its efficacy in stabilizing oxygenation and reducing the need for mechanical ventilation, contributing to better pulmonary outcomes. Additionally, HFNO therapy is associated with enhanced patient comfort, as it is less invasive and allows for easier interaction with caregivers compared to traditional methods. It also minimizes the risk of nasal trauma and other complications associated with endotracheal intubation and nasal continuous positive airway pressure (nCPAP). The review highlights the mechanisms by which HFNO supports respiratory function in neonates, including its impact on lung mechanics, airway pressure, and oxygen delivery. Furthermore, the abstract discusses the importance of appropriate flow settings, humidification levels, and patient monitoring to maximize the benefits and minimize potential adverse effects. Future research directions are suggested to optimize HFNO therapy protocols and further explore its long-term outcomes in neonatal care. This synthesis underscores HFNO as a valuable tool in the respiratory management of neonates with RDS, balancing efficacy with enhanced patient comfort.

Keyphrases: High-flow nasal oxygen (HFNO), nasal continuous positive airway pressure (nCPAP), respiratory distress syndrome (RDS)

@Booklet{EasyChair:13689,
  author = {Abill Robert},
  title = {Physiological Effects and Patient Comfort: High-Flow Nasal Oxygen Therapy in Neonates with Respiratory Distress Syndrome},
  howpublished = {EasyChair Preprint no. 13689},

  year = {EasyChair, 2024}}