Download PDFOpen PDF in browser

Development of three-dimensional physiological function imaging of biological body by transillumination imaging using near infrared light - preliminary research -

8 pagesPublished: May 15, 2020

Abstract

In biological tissue, there are different kinds of endogenous chromophores. Their absorption spectra in the optical range are sensitive to the physiological change of the animal body. In the near-infrared region (700-1200 nm wavelength), hemoglobin has a characteristic absorption spectrum which is dependent on its redox state. Therefore, the functional information inside the animal body could be obtained noninvasively by measuring the transmitted light. By detecting the change of the absorption characteristics of the animal body, the functional change inside the body can be detected in a two-dimensional transillumination image. In this paper, we propose preliminary research on developing a novel imaging modality of biological body parts. Using the two-dimensional images obtained in many different orientations, three-dimensional physiological function imaging of the biological body by transillumination could be expected. This paper presents a preliminary result in the experiment to show the feasibility of this technique.

Keyphrases: 3D reconstruction, blood vessel, deconvolution, functional imaging, near infrared, point-spread-function (PSF)., Scattering suppression, transillumination

In: Tich Thien Truong, Trung Nghia Tran, Quoc Khai Le and Thanh Nha Nguyen (editors). Proceedings of International Symposium on Applied Science 2019, vol 3, pages 11--18

Links:
BibTeX entry
@inproceedings{ISAS2019:Development_of_three_dimensional_physiological,
  author    = {Ngoc An Dang Nguyen and Phuong Anh Bui and Anh Tu Tran and Trung An Dang Nguyen and Van Chinh Nguyen and Koichi Shimizu and Trung Nghia Tran},
  title     = {Development of three-dimensional physiological function imaging of biological body by transillumination imaging using near infrared light - preliminary research -},
  booktitle = {Proceedings of International Symposium on Applied Science 2019},
  editor    = {Tich Thien Truong and Trung Nghia Tran and Quoc Khai Le and Thanh Nha Nguyen},
  series    = {Kalpa Publications in Engineering},
  volume    = {3},
  pages     = {11--18},
  year      = {2020},
  publisher = {EasyChair},
  bibsource = {EasyChair, https://easychair.org},
  issn      = {2515-1770},
  url       = {https://easychair.org/publications/paper/vvhZ},
  doi       = {10.29007/dvzs}}
Download PDFOpen PDF in browser