A knowledge management process is a collection of practices that can work effectively to benefit academicians and foster innovation at Higher Education Institutions (HEI). With the advancement in Information, Communication, and Technology (ICT) capabilities, these institutions are presented with opportunities as well as challenges to keep up with knowledge management. Together with the emergence of Learning Management Systems (LMS), institutions have an unprecedented opportunity to facilitate and improve the quality of teaching-learning resources. Many researchers have investigated the Knowledge management process integration and its implementation in HEIs. Some have also examined the benefits of LMS implementation, the barriers, and underutilization. In addition, researchers are interested in analyzing the best teaching and content delivery methods associated with LMS implementation, such as blended learning environments that integrate online and face-to-face delivery methods. This systematic review investigates knowledge management integration in HEIs and emphasizes the blended learning environment by examining the implementation of the learning management system. The review analyzes 16 studies collected from different databases between 2012 and 2021 dealing with knowledge sharing, and to a lesser extent, with knowledge creation and knowledge acquisition. A key finding of the review was that the knowledge management process could enhance an institution's ability to innovate. Through KM and LMS, an institution can transform the traditional face-to-face environment into a blended, innovative, convenient, flexible, and student-centric mode of delivery, which leads to organizational and stakeholder performance improvements. Unfortunately, the review also identified that implementation to date is not as effective as it should be.