The global health emergency situation in 2020 has accelerated the process of companies’ digital transformation. Through this process firms discovered the relevance of the new digital channel in order to manage the relationship with their customers and stakeholders. In this context, the paper wants to analyze and discuss the impact of digital channel in SMEs’ strategies. In particular, the research is conducted on Italian mid-sized companies, also known as “micro-multinational” or “pocket-multinational”, considering the key industries of Made in Italy.