The conditions of origin, development and transformation of the Donetsk and Luhansk regions of Ukraine are considered. There is an irreversible tendency to reduce the industrial potential of the coal and metallurgical industry, the collapse of the urban base. The nature and scale of the impact of the armed conflict in eastern Ukraine on the state of the engineering and planning organization in the territory of the Luhansk region is studied. The correspondence of regional typologies on the basis of function in the modern conditions of the armed conflict is analyzed. The analysis allows us to identify the following important aspects. A gradual but irreversible process of deindustrialization is recorded. The transformation of the engineering and planning organization of the territory of the Luhansk region in the conditions of the armed conflict in the East of Ukraine is a fait accompli. A new political and economic reality is being formed. The Luhansk and Donetsk regions are artificially divided. The analysis of a demographic condition, a territorial, town-planning complex testifies to discrepancy of typological signs of the area in the modern conditions. The Luhansk region is becoming a cross-border region with a dense border. It is expedient to expand the existing classification of regions by introducing certain special functions of the regional typology. In the modern conditions, in the Luhansk and Donetsk regions, a border region is formed. Along this line, the function of cross-border cooperation is complemented by the function of the border control. This function aims to limit a certain type - the fixation of the border, the mode of its crossing, strict adherence to legally established procedures. The addition of the functions of the regional typology should be taken into account in the tasks of improving the territorial - planning organization of the Luhansk region.