The article is devoted to the use of mixed reality facilities in the training of future sea transport professionals. It says that one of the means of improving training technologies in maritime education is the use of simulators. The work lists the definitions of “mixed reality” term, which most of the scientists define as the merging of real and virtual worlds to produce new environments and visualizations. The article also describes the use of virtual-real training vessel in Kherson State Maritime Academy, which includes 19 laboratories, 16 simulators and 21 classrooms. The list of the main laboratories and their functions is given. The advantages of virtual-real training vessel built by means of mixed reality are described. The part of simulator exercise list is given. The article describes the results of experimental study of future navigators’ professional navigational competence development with mixed reality simulation technologies. The authors made the conclusion that the use of mixed reality facilities allows to optimize the process of professional training and contributes to the effective formation of professional navigation competence of maritime specialists.