Recent literature in the context of organ donation suggests that the dissemination of organ donation information on social media should be emphasized to increase the registration of organ donors. Therefore, the current study aims to investigate the impact of disseminating organ donation information on social media towards the intention to register as organ donors. In the meantime, the role of family discussion also suggested plays a significant factor in the process to register as organ donors. To conduct this study, a sample of undergraduate university students that comprise the public universities in Malaysia was selected. Next, the data obtained among the sample were analyzed using SmartPLS version 3.3.3. The result suggests that the information adoption positively contributes to the intention to register as organ donors. Furthermore, the result also reveals that the family discussion moderates the relationship between information adoption and intention to register as organ donors. The current research contributes by providing strong evidence to formulate a sound marketing strategy associated with organ donation matters.