The technology advancement in the era of Industry 4.0 has enabled the offsite monitoring of patients and allowed the public to keep track on their health condition effectively. The advancement of healthcare technology also enabled wearable medical devices (WMD) to gain the limelight as the fastest growing technology in the healthcare industry. Driving by the potential benefit in combatting the non-communicable disease (NCD) issue and the market opportunity of WMD in Malaysia, especially the younger generation (Gen Y and Z), this study aimed to explore and compare the factors influencing the IU of WMD among the younger generation in Malaysia. The results and the potential implications of the findings has been further discussed in the context.