The issue of energy-saving and energy efficiency is actual at the present-day development of Ukraine’s economy. The imperfective system of energy ensuring as the result of inefficient energy resources utilization is a characteristic feature of the state. The analysis of ensuring energy resources applied to Dnipropetrovsk Region as one of the leading industrial regions of the country is presented in the article. The availability of reserves and production of fuel resourceswas analyzed in it.Distinctive features of energy resources consumption with the aim of assessment general and partial indexes of energy ensuring and fuel power-intensity of the region’s economic complex are highlighted in the work. The tendencies and perspectives of energy consumption development of the Dnipropetrovsk Region were analyzed herewith.