In this research, we study the interference cancellation capabilities of receivers and transmitters in multiple-input-multiple-output (MIMO) systems using theoretical calculations and numerical simulations in Quadriga. We study so-called Reduced Channel Zero-Forcing (RCZF) class of precoding as well as Minimum MSE Interference Rejection Combiner (MMSE-IRC) and QR Maximum Likelihood Detection (QR-MLD) receivers. The precodings from the RCZF class are widely used in practice and include for example Zero-Forcing (ZF), Regularized Zero-Forcing (RZF) and Iteratively Weighted MMSE precodings. Our theoretical and experimental results confirm that MMSE-IRC and QR-MLD receivers in combination with the RCZF precoding provide complete interference suppression asymptotically.