Ensuring the integrity and security of online assessments remains a critical challenge for higher education institutions, particularly in regions where infrastructure constraints, data sovereignty requirements, and high student volumes converge. This paper presents a case study on deploying a containerized Moodle environment, hosted locally and integrated with Safe Exam Browser (SEB), to deliver secure, large-scale online examinations in an African university context. The system architecture leverages Docker containerization managed through Portainer for modular service deployment, rapid scaling, and simplified maintenance, while SEB enforces strict proctoring conditions including full-screen lockdown, restricted resource access, and controlled network connectivity. Load testing validated the system’s performance with over 3,000 concurrent secure sessions, maintaining an average response time under 2.5 seconds and uptime above 99.8% during peak examination periods. Security was embedded throughout the design with TLS encryption, network segmentation, role-based access controls, and isolated exam servers, ensuring compliance with institutional cybersecurity frameworks and national data protection regulations. The local hosting approach enhanced data privacy, reduced reliance on external cloud providers, and achieved estimated cost savings of over 70% compared to commercial LMS hosting. Findings demonstrate that combining containerized infrastructure with SEB-based secure assessment workflows yields a scalable, cyber-resilient, and policy-aligned model for African institutions seeking to modernize examination delivery while safeguarding academic integrity.