HSB'14 – 3rd International Workshop on Hybrid Systems and Biology
July 23-24, 2014 · Vienna, Austria
Important Dates
Paper submission deadline | March 10, 2014 |
Author Notification | May 8, 2014 |
Camera-ready versions for the proceedings | October 1, 2014 |
Aims and Scope
Systems biology aims at providing a system-level understanding of biological systems by unveiling their structure, dynamics, and control methods. Living systems are intrinsically multi-scale in space, in organization levels and in time; they also exhibit a mixture of deterministic and stochastic behaviors. It is therefore very difficult to model them in a homogeneous framework, for instance, by systems of differential equations or by discrete-event systems. Furthermore, such models are often not easily amenable to formal analysis and their simulations at the organ or even the cell level are frequently impractical. Indeed, an important open problem is finding appropriate computational models that scale-up well for both simulation and formal analysis of biological processes.
Hybrid modeling techniques, combining discrete and continuous processes, are gaining more and more attention in systems biology. They have been applied to successfully capture the behavior of several biological complex systems, including genetic regulatory networks, metabolic reactions, signaling pathways as well as higher level models of tissues and organs. As the challenges of scale and intrinsic inhomogeneity are coming to the forefront of systems biology efforts, they highlight the value of a hybrid dynamical modeling paradigm that integrates mathematical models that address distinct spatio-temporal scales and subsystems.
In this spirit, the scope of the HSB workshop is the general area of dynamical models in Biology with an emphasis onhybrid approaches, which are not restricted to a narrow class of mathematical models, and which take advantage of techniques developed separately in different sub-fields.
Topics of interest include, but are not limited to:
- Hybrid models of metabolic, signaling, and genetic regulatory networks in living cells
- Hybrid models of tissues, organs; physiological models
- Biological applications of analysis techniques from hybrid systems theory (reachability computation, model checking, abstract interpretation, bifurcation theory, stability and sensitivity analysis)
- Parametric and non-parametric system identification techniques (learning models from experimental data)
- Efficient techniques for combined (stochastic/deterministic, spatial/non-spatial) simulations for biological models
- Hybrid modeling languages for biological systems; analysis and simulation tools
- Models coping with incomplete and uncertain information; stochastic hybrid systems
- Hierarchical hybrid systems for multi-scale analysis
- Abstraction, approximation and model reduction techniques
- Hybrid systems modeling for synthetic biology and control of biological systems
We solicit the submission of unpublished results that address theoretical and/or applied aspects of hybrid modeling techniques in systems biology. Submissions accepted as full papers will be published in the Springer LNCS/LNBI series.
Paper Submission
Full papers should be no more than 15 pages long, typesetted in the LNCS style.
Electronic submissions of full-length papers (in PDF format), will be done through the online submission system.
Location
HSB 2014 will be a two-day satellite workshop of CAV 2014, Conference on Computer-aided Verification, the 26th International which is part of the Vienna Summer of Logic.
Invited Speakers
- David Harel, The Weizmann Institute of Science
- Eshel Ben-Jacob, Tel-Aviv University
Program co-Chairs
- Ádám Halász, West Virginia University, USA
- Oded Maler, VERIMAG/CNRS, Grenoble, France
Local Organization and Publicity Chair
- Ezio Bartocci, Vienna University of Technology, Austria
Program Committee
- Marco Antoniotti, University of Milano Bicocca, Italy
- Ezio Bartocci, Vienna University of Technology, Austria
- Gregory Batt, INRIA Rocquencourt, France
- Luca Bortolussi, Univerity of Trieste, Italy
- Thao Dang, VERIMAG/CNRS, Grenoble, France
- Vincent Danos, CNRS/Université Paris-Diderot, France
- Hidde de Jong, INRIA Grenoble - Rhône-Alpes, France
- Alexandre Donzé, UC Berkley, USA
- François Fages, INRIA Rocquencourt, France
- Eric Fanchon, TIMC-IMAG Laboratory, Grenoble, France
- Hans Geiselmann, University of Grenoble, France
- Radu Grosu, Vienna University of Technology, Austria
- Ádám Halász, West Virginia University, USA - (co-chair)
- Thomas Henzinger, IST, Austria
- Jane Hillston, University of Edinburgh, UK
- Agung Julius, Rensselaer Polytechnic Institute, USA
- Heinz Koeppl, ETH Zurich, Switzerland
- Hillel Kugler, Microsoft Research, UK
- Marta Kwiatkowska, Oxford University, UK
- Pietro Lio, University of Cambridge, UK
- Oded Maler, VERIMAG/CNRS, Grenoble, France - (co-chair)
- Bud Mishra, NYU, USA
- Chris Myers, University of Utah, USA
- Casian Pantea, West Virginia University, USA
- Carla Piazza, University of Udine, Italy
- David Šafránek, Masaryk University, Czech Republic
- Ricardo Sanfelice, University of Arizona, USA
- P.S. Thiagarajan, National University of Singapore, Singapore
- Verena Wolf, Saarland University, Germany
Steering Committee
- Ezio Bartocci, Vienna University of Technology, Austria
- Luca Bortolussi, Univerity of Trieste, Italy
- Thao Dang, VERIMAG/CNRS, Grenoble, France
- Ádám Halász, West Virginia University, USA
- Oded Maler, VERIMAG/CNRS, Grenoble, France
- Carla Piazza, University of Udine, Italy