PROGRAM
Days: Monday, April 8th Tuesday, April 9th Wednesday, April 10th
Monday, April 8th
View this program: with abstractssession overviewtalk overview
09:10-09:50 Session 2: Keynote
Chair:
Location: Main lecture room
09:10 | (Keynote) From small (and not so small) animals to humans: Lessons learned from translational studies using photon and proton radiation beams at Penn (abstract) |
09:50-10:51 Session 3: Minibeams & FLASH
Chair:
Location: Main lecture room
09:50 | (Invited) Minibeam Radiation therapy (abstract) |
10:15 | Long-term skin side effects of FLASH proton radiotherapy compared to conventional radiotherapy (abstract) |
10:27 | Investigating the tumor control dose (TCD50) of microbeam radiation therapy (MRT) compared to conventional radiation therapy (CRT) of human tumor xenografts in nude mice (abstract) |
10:39 | FLASH and SFRT: Revisiting Spatial and Temporal factors in RT in the laboratory setting. (abstract) |
10:51-11:15Coffee Break & Exhibition
11:15-12:40 Session 4: Targeting & Translation
Chair:
Location: Main lecture room
11:15 | (Invited) SFRT and TFRT with a small animal radiotherapy platform (abstract) PRESENTER: Martin Pruschy |
11:40 | Radiodynamic therapy with porphysome nanoparticles in a syngeneic mouse sarcoma model (abstract) PRESENTER: Etain Davidson |
11:52 | Developing a preclinical mouse model to study image-guided stereotactic ablative radiotherapy and systemic treatment in Liver Cancer (abstract) |
12:04 | Targeting VEGF-A in an immunocompetent orthotopic mouse model of mesenchymal glioblastoma improves anti-tumorigenicity and decreases proinflammatory response in normal brain tissue after fractionated radiotherapy (abstract) PRESENTER: Michael Orth |
12:16 | Targeting radioresistance in different pancreatic tumor models (abstract) |
12:28 | Preclinical development of physical and biological strategies to reduce radiation-induced cardiac toxicity (abstract) |
12:40-13:00 Session 5: Discussion Session I - Moderators: Eric Diffenderfer, Thorsten Frenzel
Location: Main lecture room
13:00-14:15Lunch Break
13:00-14:15 Session 6: Poster Session (authors present for questions)
Location: Break & Exhibition space
Investigation of TLD Fading at Body Temperature: Implications for Long-Term Radiation Dosimetry (abstract) |
Preclinical mini-beam radiotherapy of a glioblastoma model (abstract) |
Understanding myeloid and lymphoid cell heterogeneity in metastasis following radiotherapy (abstract) |
14:15-15:15 Session 7: Technology and Imaging
Chair:
Location: Main lecture room
14:15 | Precision of treatment couch, CB-CT and micro-CB-CT of a small animal radiotherapy device (abstract) |
14:27 | Efforts among the UK professional community in support of the standardisation of dosimetry aspects of preclinical and radiobiological research. (abstract) |
14:39 | Assessment and mitigation of geometric distortions in Magnetic Resonance images for pre-clinical irradiation at 15.2T (abstract) |
14:51 | SAPPHIRE - Establishment of Small Animal Proton and PHoton Image-guided Radiation Experiments (abstract) |
15:03 | Preclinical Oxygen Imager for Oxygen-guided Radiation Therapy in Murine Tumor Models (abstract) |
15:15-15:45Coffee Break & Exhibition
15:45-17:30 Session 8: News from Vendors
Chair:
Location: Main lecture room
15:45 | Precision X-Ray: Innovation Updates |
16:00 | From Benchtop to FLASH |
16:15 | micro-RayStation update |
16:30 | Molecubes: The value of PET, SPECT and CT imaging in small animal research |
16:45 | Medscint: Challenges and promises of using scintillation detectors for small animal irradiators |
17:00 | SmART Scientific Solutions: Developments in preclinical irradiation planning: SmART-RAD, SmART-Contour, SmART-FLASH PRESENTER: Nick Staut |
17:30-17:50 Session 9: Discussion Session II - Moderators: Julie Lascaut, Karl Butterworth
Location: Main lecture room
17:50-23:59Free Evening
Tuesday, April 9th
View this program: with abstractssession overviewtalk overview
09:00-10:25 Session 10: Normal Tissue & Tumors
Chair:
Location: Main lecture room
09:00 | (Invited) Towards personalized dose fractionation in radiotherapy: Investigating fractionation-dependent recovery in preclinical models of breast cancer (abstract) |
09:25 | Radiation-induced cardiotoxicity: model development to test early detection with molecular imaging (abstract) |
09:37 | Development of murine radiation-induced lymphopenia models to investigate how lymphopenia influences treatment outcome (abstract) |
09:49 | Orthotopic glioblastoma models for evaluation of the microscopic tumor spread (abstract) |
10:01 | Characterization of tumor- and chemoradiotherapy-induced cachexia in an orthotopic lung cancer mouse model. (abstract) |
10:13 | Captopril mitigates radiation-induced cardiopulmonary side-effects only if the lung is spared (abstract) PRESENTER: Peter van Luijk |
10:25-10:55Coffee Break & Exhibition
10:55-11:56 Session 11: FLASH & Minibeams
Chair:
Location: Main lecture room
10:55 | (Invited) FLASH Radiation Research with small animals in Oxford (abstract) |
11:20 | Real-time dose measurement during minibeam radiotheraphy using radioluminescence imaging (abstract) |
11:32 | Verification of a dynamic dose painting technique for pre-clinical irradiation with synchrotron-based ultra-high dose rate x-ray fields (abstract) |
11:44 | Establishing traceable dosimetry for the SARRP FLASH (abstract) |
11:56-12:30 Session 12: Discussion Session III - Moderators: Martin Pruschy, Constantinos Koumenis
Location: Main lecture room
12:30-13:45Lunch Break
13:45-15:09 Session 13: Dosimetry & Technology & Imaging
Chair:
Location: Main lecture room
13:45 | Development of End-to-End Preclinical Treatment Verification Procedures, Traceable to NPL Air Kerma Primary Standard (abstract) |
13:57 | Use of a versatile and robust mouse phantom for end-to-end testing of irradiation protocols (abstract) |
14:09 | A comparative analysis of preclinical computed tomography radiomics using cone-beam and micro-CT scanners (abstract) PRESENTER: Brianna Kerr |
14:21 | Mitotic enrichment as an efficient radiosensitization strategy for intracranial tumors (abstract) |
14:33 | Using Complementary Anatomical Information from CT to Improve the Performance of Bioluminescence Tomography Reconstruction for Glioblastoma Multiforme (abstract) |
14:45 | Plan study and dosimetric verification of image-guided mouse cranio-spinal irradiations (abstract) |
14:57 | Image-guided radiation-induced injury models using the SARRP (abstract) |
15:09-15:40Coffee Break & Exhibition
15:40-17:29 Session 14: Ion Beams
Chair:
Location: Main lecture room
15:40 | (Invited) Ten years of preclinical (in vivo) experimentation at UPTD (abstract) |
16:05 | SIRMIO: A novel platform for precision image-guided proton irradiation of small animals (abstract) |
16:17 | A deterministic proton dose engine with Monte Carlo accuracy for preclinical applications (abstract) |
16:29 | Development of an integrated proton beam delivery and animal translation system using a Small Animal Radiation Research Platform (abstract) |
16:41 | Dose and LET distribution uncertainties in an IGRT workflow for pre-clinical proton research (abstract) |
16:53 | Cell specific analysis of microglia response after proton-irradiated mouse brains (abstract) |
17:05 | Impact of deep learning-based segmentation methods on proton dose distribution in small animals (abstract) |
17:17 | Advanced particle irradiations for high-precision image guided preclinical research (abstract) |
17:29-17:50 Session 15: Discussion Session IV - Moderators: Katia Parodi, Antje Dietrich
Location: Main lecture room
19:30-23:00Conference Dinner - Venue: Restaurant 7 Schaken
Wednesday, April 10th
View this program: with abstractssession overviewtalk overview
09:00-10:00 Session 16: Normal Tissues and Tumors
Chair:
Location: Main lecture room
09:00 | Investigating the spatiotemporal neuroinflammatory response of half-brain irradiation in a murine model using 18F-FEPPA PET (abstract) |
09:12 | Age-induced and ionizing radiation-triggered changes of glial makers in the brain of rats (abstract) |
09:24 | Development of Clinically Relevant Radiotherapy Methods for Measuring Survival Benefits and Late Effects of Radiosensitising Drugs in Mouse Models of Medulloblastoma (abstract) |
09:36 | Development of preclinical cone-beam CT imaging biomarkers to characterise tumour heterogeneity, radiation response and the early detection of metastasis (abstract) |
09:48 | Dose-dependent changes in cardiac function, deformation and remodelling in a preclinical model of heart base irradiation (abstract) |
10:00-10:30Coffee Break & Exhibition
10:30-11:43 Session 17: Dosimetry&Imaging&Technology
Chair:
Location: Main lecture room
10:30 | (Invited) Ionoacoustics-based dose monitoring in pre-clinical proton beam therapy (abstract) |
10:55 | New X-Ray Irradiators for Research: Experience with the USA Cesium Irradiator Replacement Project (abstract) |
11:07 | Towards standardized commissioning data for the Small Animal Radiological Research Platform (SARRP) (abstract) |
11:19 | Automated quantification of tumor volume and characterization of cachexia in a novel orthotopic lung cancer mouse model and patients (abstract) |
11:31 | An Open-Source Python Pipeline for Multi-Modal Feature Extraction for Data Science in Pre-Clinical Research (abstract) |