SMALL ANIMALS 2024: 6TH CONFERENCE ON SMALL ANIMAL PRECISION IMAGE-GUIDED RADIOTHERAPY
PROGRAM

Days: Monday, April 8th Tuesday, April 9th Wednesday, April 10th

Monday, April 8th

View this program: with abstractssession overviewtalk overview

09:10-09:50 Session 2: Keynote
09:10
(Keynote) From small (and not so small) animals to humans: Lessons learned from translational studies using photon and proton radiation beams at Penn (abstract)
09:50-10:51 Session 3: Minibeams & FLASH
09:50
(Invited) Minibeam Radiation therapy (abstract)
10:15
Long-term skin side effects of FLASH proton radiotherapy compared to conventional radiotherapy (abstract)
10:27
Investigating the tumor control dose (TCD50) of microbeam radiation therapy (MRT) compared to conventional radiation therapy (CRT) of human tumor xenografts in nude mice (abstract)
10:39
FLASH and SFRT: Revisiting Spatial and Temporal factors in RT in the laboratory setting. (abstract)
10:51-11:15Coffee Break & Exhibition
11:15-12:40 Session 4: Targeting & Translation
11:15
SFRT and TFRT with a small animal radiotherapy platform
11:40
Radiodynamic therapy with porphysome nanoparticles in a syngeneic mouse sarcoma model (abstract)
PRESENTER: Etain Davidson
11:52
Developing a preclinical mouse model to study image-guided stereotactic ablative radiotherapy and systemic treatment in Liver Cancer (abstract)
12:04
Targeting VEGF-A in an immunocompetent orthotopic mouse model of mesenchymal glioblastoma improves anti-tumorigenicity and decreases proinflammatory response in normal brain tissue after fractionated radiotherapy (abstract)
12:16
Targeting radioresistance in different pancreatic tumor models (abstract)
12:28
Preclinical development of physical and biological strategies to reduce radiation-induced cardiac toxicity (abstract)
13:00-14:15Lunch Break
13:00-14:15 Session 6: Poster session (authors present for questions)
Investigation of TLD Fading at Body Temperature: Implications for Long-Term Radiation Dosimetry (abstract)
Preclinical mini-beam radiotherapy of a glioblastoma model (abstract)
Understanding myeloid and lymphoid cell heterogeneity in metastasis following radiotherapy (abstract)
14:15-15:15 Session 7: Technology and Imaging
14:15
Efforts among the UK professional community in support of the standardisation of dosimetry aspects of preclinical and radiobiological research. (abstract)
14:27
Assessment and mitigation of geometric distortions in Magnetic Resonance images for pre-clinical irradiation at 15.2T (abstract)
14:39
SAPPHIRE - Establishment of Small Animal Proton and PHoton Image-guided Radiation Experiments (abstract)
14:51
Preclinical Oxygen Imager for Oxygen-guided Radiation Therapy in Murine Tumor Models (abstract)
15:03
Precision of treatment couch, CB-CT and micro-CB-CT of a small animal radiotherapy device (abstract)
15:15-15:45Coffee Break & Exhibition
15:45-17:30 Session 8: News from Vendors
15:45
PXI
16:00
XStrahl
16:15
micro-RayStation update
16:30
Molecubes
16:45
Medscint: Challenges and promises of using scintillation detectors for small animal irradiators
17:00
SmART Scientific Solution: XXXX
17:50-23:59Free Evening
Tuesday, April 9th

View this program: with abstractssession overviewtalk overview

09:00-10:25 Session 10: Normal Tissue & Tumors
09:00
Invited Kirsten Lauber
09:25
Radiation-induced cardiotoxicity: model development to test early detection with molecular imaging (abstract)
09:37
Development of murine radiation-induced lymphopenia models to investigate how lymphopenia influences treatment outcome (abstract)
09:49
Orthotopic glioblastoma models for evaluation of the microscopic tumor spread (abstract)
10:01
Characterization of tumor- and chemoradiotherapy-induced cachexia in an orthotopic lung cancer mouse model. (abstract)
10:13
Captopril mitigates radiation-induced cardiopulmonary side-effects only if the lung is spared (abstract)
PRESENTER: Peter van Luijk
10:25-10:55Coffee Break & Exhibition
10:55-11:56 Session 11: FLASH & Minibeams
10:55
(Invited) FLASH Radiation Research with small animals in Oxford (abstract)
11:20
Real-time dose measurement during minibeam radiotheraphy using radioluminescence imaging (abstract)
11:32
Verification of a dynamic dose painting technique for pre-clinical irradiation with synchrotron-based ultra-high dose rate x-ray fields (abstract)
11:44
Establishing traceable dosimetry for the SARRP FLASH (abstract)
12:30-13:45Lunch Break
13:45-15:09 Session 13: Dosimetry & Technology & Imaging
13:45
Development of End-to-End Preclinical Treatment Verification Procedures, Traceable to NPL Air Kerma Primary Standard (abstract)
13:57
Use of a versatile and robust mouse phantom for end-to-end testing of irradiation protocols (abstract)
14:09
A comparative analysis of preclinical computed tomography radiomics using cone-beam and micro-CT scanners (abstract)
PRESENTER: Brianna Kerr
14:21
Mitotic enrichment as an efficient radiosensitization strategy for intracranial tumors (abstract)
14:33
A multi-channel deep learning model to enable the complementary use of CT and BLI to improve the bioluminescence tomography reconstruction accuracy (abstract)
14:45
Plan study and dosimetric verification of image-guided mouse cranio-spinal irradiations (abstract)
14:57
Image-guided radiation-induced injury models using the SARRP (abstract)
15:09-15:40Coffee Break & Exhibition
15:40-17:29 Session 14: Ion beams
15:40
(Invited) Ten years of preclinical (in vivo) experimentation at UPTD (abstract)
16:05
SIRMIO: A novel platform for precision image-guided proton irradiation of small animals (abstract)
16:17
A deterministic proton dose engine with Monte Carlo accuracy for preclinical applications (abstract)
16:29
Development of an integrated proton beam delivery and animal translation system using a Small Animal Radiation Research Platform (abstract)
16:41
Dose and LET distribution uncertainties in an IGRT workflow for pre-clinical proton research (abstract)
16:53
Cell specific analysis of microglia response after proton-irradiated mouse brains (abstract)
17:05
Impact of deep learning-based segmentation methods on proton dose distribution in small animals (abstract)
17:17
Advanced particle irradiations for high-precision image guided preclinical research (abstract)
19:30-21:00Conference Dinner - XXXX
Wednesday, April 10th

View this program: with abstractssession overviewtalk overview

09:00-10:12 Session 16: normal tissue and tumors
09:00
Investigating the spatiotemporal neuroinflammatory response of half-brain irradiation in a murine model using 18F-FEPPA PET (abstract)
09:12
Mapping the impact of radiotherapy and immune checkpoint inhibition on the tumour immune microenvironment in head and neck cancer (HNSCC) (abstract)
09:24
Age-induced and ionizing radiation-triggered changes of glial makers in the brain of rats (abstract)
09:36
Development of Clinically Relevant Radiotherapy Methods for Measuring Survival Benefits and Late Effects of Radiosensitising Drugs in Mouse Models of Medulloblastoma (abstract)
09:48
Development of preclinical cone-beam CT imaging biomarkers to characterise tumour heterogeneity, radiation response and the early detection of metastasis (abstract)
10:00
Dose-dependent changes in cardiac function, deformation and remodelling in a preclinical model of heart base irradiation (abstract)
10:12-10:45Coffee Break & Exhibition
10:45-11:58 Session 17: Dosimetry&Imaging&Technology
10:45
Invited Julie Lascaud
11:10
Fast Monte Carlo Comparison of Static Arc, 3D-CRT, and IMRT for Oxygen-Guided Radiotherapy in a Mouse Leg Fibrosarcoma Case (abstract)
PRESENTER: Rajit Tummala
11:22
Towards standardized commissioning data for the Small Animal Radiological Research Platform (SARRP) (abstract)
11:34
Automated quantification of tumor volume and characterization of cachexia in a novel orthotopic lung cancer mouse model and patients (abstract)
11:46
An Open-Source Python Pipeline for Multi-Modal Feature Extraction for Data Science in Pre-Clinical Research (abstract)