PROGRAM
Days: Monday, May 23rd Tuesday, May 24th Wednesday, May 25th Thursday, May 26th Friday, May 27th
Monday, May 23rd
View this program: with abstractssession overviewtalk overview
08:00-09:00 Session 1
Refreshments and Onsite Registration
09:00-09:45 Session 2
Introduction to Single Cell Genomics (Dr. Egon Ranghini, 10X Genomics)
Chair:
| 09:00 | Trailblazing the future of spatial biology (abstract) |
10:00-11:00 Session 4
Applications, limitations, and future directions of single cell technology for eQTL mapping (Virtual Panelist: Dr. Xia Yang, University of California Los Angeles)
Chair:
| 10:00 | Integrative systems analysis, applications, and challenges of single cell multiomics (abstract) |
11:15-11:30Lunch Break
11:30-12:30 Session 6
Introduction to Spatial Genomics (Dr. Egon Ranghini, 10X Genomics)
Chair:
| 11:30 | Reveal the full complexity of cellular diversity, cell by cell (abstract) |
12:45-13:45 Session 8
Applications, limitations, and future directions of spatial cell technology for eQTL mapping (Virtual Panelists: Drs. Kristen Maynard and Leo Collado, Lieber Institute for Brain Development)
Chair:
| 12:45 | Spatial gene expression in the human brain: applications, limitations, and future directions (abstract) |
14:00-15:45 Session 10
Trainee Workshop: Networking for Success in Science (Chair: Kristin Scaplin)
Chair:
15:45-16:00Break
16:00-18:00 Session 11
Trainee Workshop: Trainee Workshop: Networking for Success in Science (Chair: Kristin Scaplin)
Chair:
Tuesday, May 24th
View this program: with abstractssession overviewtalk overview
09:00-11:00 Session 14
Symposium I. Mapping the brain: Neuroimaging and connectome approaches to study genetic variation in brain function, structure, and behavior
Speakers: Al Johnson, Neda Jahanshad, Sofie Valk, Antoine Beauchamp
Chairs: Dr. Clyde Francks and Co-Chair: Dr. Megan Mulligan
Chair:
| 09:00 | HiDiver: Merging Magnetic Resonance and Light Sheet Microscopy with 3D Labels (abstract) |
| 09:25 | Whole-brain comparison of rodent and human brains using spatial transcriptomics (abstract) |
| 09:50 | Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex (abstract) |
| 10:15 | Enhancing Neuro Imaging Genetics through Meta Analysis - Recent GWAS updates and new initiatives from the ENIGMA Consortium (abstract) |
| 10:40 | Genetic architecture of the white matter connectome of the human brain (abstract) |
11:00-11:15Break
11:15-12:15 Session 15
Outstanding Travel Awardees
Chairs:
Amy Lasek and Paul Meyer
| 11:15 | Towards the Neural Basis of Individual Differences in the Exploratory Behavior of Zebrafish (abstract) |
| 11:30 | The thermo-balancing act: The molecular, cellular, and behavioral mechanisms underlying thermal homeostasis in larval Drosophila (abstract) |
| 11:45 | Inbred mouse strain differences in adolescent hippocampal learning and gene expression after acute ethanol exposure (abstract) |
| 12:00 | Behavioral differences in neonatal opioid withdrawal syndrome (NOWS) model phenotypes in FVB substrains following perinatal morphine exposure (abstract) |
12:15-13:00Lunch Break
13:00-15:00 Session 16
Symposium 2. Genetic studies of drug addiction-related traits in outbred rats
Speakers: Abe Palmer, Paul Meyer, Hao Chen, Francesca Telese, Alexandria Szalanczy
Chair: Dr. Oksana Polesskaya
Chair:
| 13:00 | Overview of the NIDA center for genetic studies of drug abuse in outbred rats (abstract) |
| 13:25 | Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders (abstract) |
| 13:50 | Genome-Wide Association Study Identifies Multiple Loci for Cue-Responsivity Measured During a Pavlovian Conditioned Approach Paradigm. (abstract) |
| 14:15 | Cell type-specific transcriptional and regulatory mechanisms associated with addiction-related behaviors in HS rats (abstract) |
| 14:40 | Keratinocyte-associated protein 3 may participate in the stress response to impact adiposity and behavior (abstract) |
15:15-15:30Break
15:30-17:30 Session 17
Poster Session I
P1 Genetic Variation in Cocaine Preference in the Drosophila melanogaster Genetic Reference Panel (abstract) |
P3 Diet and Parent-of-Origin Dependent Effects of Body Composition, Locomotor Activity, and AgRP Neuronal Activity are Sex Specific in PWK/PhJ x C57BL/6J F1 Mice (abstract) |
Participation of the neurodevelopmental disorder associated gene MYT1L in motor function and sensory responsivity. (abstract) |
P7 Beyond bold versus shy: zebrafish exhibit multiple distinct behavioral types during exploration of a novel tank. (abstract) |
P9 Decoding the Role of Synpatically Translated RNA Binding Proteins in Associative Memory (abstract) |
P11 Modelling seizure-induced and extinction learning-dependent neuronal activation in pediatric epilepsy (abstract) |
P13 Neural circuits for low and moderate alcohol responses in Drosophila melanogaster (abstract) |
P15 The relationship between host genetics, microbiome composition and addictive or addictive-predictive behavior in Diversity Outbred mice. (abstract) |
P17 The Rat Genome Database (RGD) facilitates neurological disease genes research and cross-species analyses (abstract) |
P19 Characterization of novel clinically-relevant behavioral phenotypes in young adult Mucopolysaccharisosis IIIB mice (abstract) |
P21 Gene expression profiles in HS-CC founder strains (abstract) |
P23 Measuring negative affective withdrawal in CFW mice: Implications for GWAS (abstract) |
P25 Interspecific Drosophila Recombinant Inbred Lines as a Tool to Determine Genetic Basis of Neophilia (abstract) |
P27 Making data from the Center for GWAS in outbred rats FAIR (abstract) |
P29 Effect of Chronic Stress on Inflammation in the hippocampus (abstract) |
P31 Investigating the role of Methylglyoxal as a GABAA Agonist through Glyoxalase 1 Manipulation (abstract) |
P33 Alcohol-Induced Alternative Splicing in Drosophila Memory Circuits (abstract) |
P35 Effects of cocaine on brain and behavior: an evaluation of the fragile X mental retardation protein in dopamine D1 receptor-expressing cells of the striatum (abstract) |
P37 Evaluating the convergent evolution of genes associated with pair bonding in mammals (abstract) |
P39 The importance of genetic background for model organism genetics, with implications for Alzheimer’s disease and longevity (abstract) |
P41 Development of gait abnormalities and tremor in a mouse model of Krabbe disease (abstract) |
P43 Exercise Promotes Sex-Specific Resilience to The Effects of Chronic Stress (abstract) |
P45 Selecting mice for high cognitive abilities (abstract) |
P47 Behavioral differences in neonatal opioid withdrawal syndrome (NOWS) model phenotypes in FVB substrains following perinatal morphine exposure (abstract) |
P49 Predicting genotype of fruit flies from locomotive trajectories using supervised Machine Learning (abstract) |
Wednesday, May 25th
View this program: with abstractssession overviewtalk overview
08:00-09:00 Session 18
Refreshments and Onsite Registration
09:00-10:00 Session 19
Distinguished Scientist Award
Elissa Chesler
Chair:
| 09:00 | Distinguished Investigator Award Presentation: Dr. Elissa Chesler (abstract) |
10:00-10:15Break
10:15-12:15 Session 20
Symposium 3. Behavior Quantification using Machine Learning: Challenges and Opportunities
Speakers: Sara Lisanby, Ann Kennedy, Eric Yttri, Vivek Kumar
Chair: Dr. Vivek Kumar
Chair:
| 10:15 | Brain-Behavior Quantification and Synchronization (abstract) |
| 10:40 | B-SOiD: Automated extraction of meaningful behaviors from any position data without user bias (abstract) |
| 11:05 | Establishing benchmarks for better behavior quantification (abstract) |
| 11:30 | Integrated, machine learning based advanced phenotyping platform for the laboratory mouse (abstract) |
12:15-13:00Lunch Break
13:00-14:00 Session 21
Young Investigator Award
Dr. Monica Dus
Chair:
| 13:00 | Confection Confusion: the Interplay between diet, genes, and taste (abstract) |
14:00-14:15Break
14:15-16:15 Session 22
Symposium 4
Selected talks
Chairs:
| 14:15 | Rapid Assessment of the Temporal Function and Phenotypic Reversibility of Neurodevelopmental Disorder Risk Genes using Auxin-Inducible Degradation in C. elegans (abstract) |
| 14:30 | Transcriptional and chromatin-based reprogramming of behaviors with social experience and pheromone signaling (abstract) |
| 14:45 | The automated social operant task: a quantitative measure of social motivation in mice. (abstract) |
| 15:00 | Role for the poly r(C)-binding protein 1 (PCBP1) in altered RNA splicing in the hippocampus of rats during withdrawal from chronic ethanol exposure and human subjects with AUD (abstract) |
| 15:15 | PDZD8 Disruption Causes Cognitive Impairment in Humans and Mice (abstract) |
| 15:30 | Function of the BN2 neurons in a neural circuit of the adult fruit fly (abstract) |
| 15:45 | Genetic and non-genetic contributors to behavioral differences among inbred mouse substrains (abstract) |
| 16:00 | Increased social motivation, motor deficits, and anxiety-like center avoidance in a mouse model of a Williams Syndrome deletion are not the result of Gtf2ird1 expression alone. (abstract) |
16:15-16:30Break
16:30-18:30 Session 23
Poster Session II
P2 Cell adhesion molecule 2 deletion reduces impulsivity and voluntary cannabinoid intake, and impairs physiological response to THC in mice (abstract) |
P4 High Intensity Alcohol Drinking in Mice Leads to Novel Corticostriatal Gene Expression Alterations (abstract) |
P6 Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions (abstract) |
P8 Effect of Genetic Manipulation of Stress Modulators on Social Interaction in Zebrafish (abstract) |
P10 Interactions between neuronal sex determination and Hox gene specification drive the segmental specialization of neural circuits along the anterior-posterior brain axis in Drosophila (abstract) |
P12 Interindividual variation in neurological traits in response to early-life Pb exposure (abstract) |
P14 RNA-Sequencing in Heterogeneous Stock Mice Selected for Nicotine Preference (abstract) |
P16 The role of Drosophila Stat92E signaling in response to repeated alcohol exposures (abstract) |
P18 Impact of repeated alcohol exposure on neural STAT signaling activity in Drosophila (abstract) |
P20 BALB/cByJ show indiscriminate binge-like eating of both sweetened palatable food and chow compared to BALB/cJ under intermittent, limited access conditions (abstract) |
P22 Investigating genetic modifiers of vertebrate stress through genome engineering (abstract) |
P24 Daily Binge Drinking Leads to Alterations in Circadian Behavior in C57BL/6J Male and Female Mice (abstract) |
P26 A Drosophila model for the role of Williams Syndrome-related factor eIF4H in neural development and behavior (abstract) |
P28 Diazepam Effects on Anxiety-related Defensive Behavior of High and Low Open-Field Activity Inbred Mouse Strains (abstract) |
P30 A forward genetic screen of ENU-mutagenised zebrafish identifies a mutation co-segregating with impulsivity (abstract) |
P32 The methamphetamine-induced hnRNP H targetome identifies CACNA2D2 as a downstream mechanistic target underlying behavior: Pharmacological validation with pregabalin (abstract) |
P34 Location-Specific Mutations In CHD7 Induce Specific Sensorimotor Phenotypes In a Zebrafish CHARGE Syndrome Model (abstract) |
P36 Both tfbr1b and unkl impact larval zebrafish locomotor responses and may be genetic modifiers of the vertebrate stress response. (abstract) |
P38 Characterization of oxycodone use disorder phenotypes in select rat strains of the Hybrid Rat Diversity Panel (abstract) |
P40 cyfip2 controls the acoustic startle threshold (abstract) |
P42 A reduced complexity cross between BALB/c substrains identifies Zhx2 as a candidate gene underlying oxycodone metabolite brain concentration and state-dependent learning of opioid reward (abstract) |
P44 A Pair of Serotonergic Neurons Influence the Circadian Regulation of Short-Term Learning and Memory in Drosophila melanogaster (abstract) |
P46 Cocaine withdrawal in the CC/DO founder mouse strains: Interstrain variation and heritability of negative affective withdrawal (abstract) |
P48 PKA RIIα Deficiency is Associated with Altered Downstream Expression of Dopamine and Serotonin Signaling Molecules (abstract) |
P50 Genetic screen and proteomic analysis: complementary approaches for studying methamphetamine-induced behaviors in D. melanogaster (abstract) |
P52 Presynaptic Protein Interaction In Alcohol-Related Behavior In Drosophila (abstract) |
P54 Long-term effects of adolescent nicotine exposure vary by genetic background in learning, anxiety-like phenotypes and nicotine sensitivity. (abstract) |
P56 Deploying genetic diversity to explore the impact of diet-induced obesity on AgRP neuronal activity (abstract) |
P58 Increased social motivation, motor deficits, and anxiety-like center avoidance in a mouse model of a Williams Syndrome deletion are not the result of Gtf2ird1 expression alone. (abstract) |
P60 The automated social operant task: a quantitative measure of social motivation in mice. (abstract) |
Thursday, May 26th
View this program: with abstractssession overviewtalk overview
08:00-09:00 Session 24
Refreshments and Onsite Registration
08:15-08:45 Session 25
ExComm Meeting
09:00-10:00 Session 26
Presidential Lecture
Dr. Arpana Agarwal
Chair:
| 09:00 | Genome-wide Association Studies and the Gene-Brain-Behavior Pathway to Addiction (abstract) |
10:00-10:15Break
10:15-12:15 Session 27
Symposium 5. Revolutionary genomics: Third-generation sequencing and pangenome approaches to understanding genes and behavior
Speakers: Thomas Keane, Laura Saba, Tomas Fitzgerald, and Erik Garrison
Chair: Dr. David Ashbrook
Chair:
| 10:15 | Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel (abstract) |
| 10:40 | Mapping transcriptome structure diversity in rat brain and liver using single molecule RNA sequencing (abstract) |
| 11:05 | Pangenomes from many points of view (abstract) |
| 11:30 | New era of mouse genomics with a plurality of reference genomes (abstract) |
| 11:55 | Iterative ATAC-seq (assay for transposase-accessible chromatin) to home in on neurons regulating behavior. (abstract) |
12:15-13:00Lunch Break
12:15-13:15 Session 28
Business Meeting and Lunch
Friday, May 27th
View this program: with abstractssession overviewtalk overview
08:00-09:00 Session 29
Refreshments and Onsite Registration
09:00-11:00 Session 30
Symposium 6. Revealing the function of sleep from flies to humans
Speakers: Paul Shaw, Maxime Jan, Malcolm von Shantz, Nirinjini Naidoo
Chair: Dr. Rozi Andretić and Co-Chair: Dr. Kristin Hamre
Chair:
| 09:00 | Symposium: Revealing the function of sleep from flies to humans (abstract) |
| 09:25 | Cellular stress and behavior, role of the UPR in sleep and cognition (abstract) |
| 09:50 | Metabolome, transcriptome, and epigenome: the other phenotypes of sleep loss (abstract) |
| 10:15 | Defining robust sleep phenotypes for human genetic population studies (abstract) |
11:00-11:15Break
11:15-12:15 Session 31
keynote Speaker
Dr. Susan Ackerman
Chair:
| 11:15 | tRNAs, Ribosome Stalling, and Neuronal Function (abstract) |
12:15-13:00Lunch Break
13:00-15:00 Session 32
The Cerebellar Nuclei in the Limelight (at Last)
Speakers: Marylka Yoe Uusisaari, Justus Kebschull, Richard Wingate, Abigail Person
Chair: Dr. Dan Goldowitz
Chair:
| 13:00 | The cerebellar nuclei: setting the stage (abstract) |
| 13:25 | A deeply conserved cell-type set forms an archetypal cerebellar nucleus (abstract) |
| 13:50 | The evodevo of cerebellar nuclei: from temporal patterning to autistic spectrum disorder (abstract) |
| 14:15 | Cerebellar refinement of skilled movements (abstract) |
18:00-22:00
Banquet
The Jack Robinson Gallery