Days: Monday, May 23rd Tuesday, May 24th Wednesday, May 25th Thursday, May 26th Friday, May 27th

Monday, May 23rd

View this program: with abstractssession overviewtalk overview

08:00-09:00 Session 1

Refreshments and Onsite Registration

09:00-09:45 Session 2

Introduction to Single Cell Genomics (Dr. Egon Ranghini, 10X Genomics)

Trailblazing the future of spatial biology (abstract)
10:00-11:00 Session 4

Applications, limitations, and future directions of single cell technology for eQTL mapping (Virtual Panelist: Dr. Xia Yang, University of California Los Angeles)

Integrative systems analysis, applications, and challenges of single cell multiomics (abstract)
11:15-11:30Lunch Break
11:30-12:30 Session 6

Introduction to Spatial Genomics (Dr. Egon Ranghini, 10X Genomics)

Reveal the full complexity of cellular diversity, cell by cell (abstract)
12:45-13:45 Session 8

Applications, limitations, and future directions of spatial cell technology for eQTL mapping (Virtual Panelists: Drs. Kristen Maynard and Leo Collado, Lieber Institute for Brain Development)

Spatial gene expression in the human brain: applications, limitations, and future directions (abstract)
14:00-15:45 Session 10

Trainee Workshop: Networking for Success in Science (Chair: Kristin Scaplin)

16:00-18:00 Session 11

Trainee Workshop: Trainee Workshop: Networking for Success in Science (Chair: Kristin Scaplin)


Opening Reception

Tuesday, May 24th

View this program: with abstractssession overviewtalk overview

08:00-09:00 Session 12

Refreshments and Onsite Registration

09:00-11:00 Session 14

Symposium I. Mapping the brain: Neuroimaging and connectome approaches to study genetic variation in brain function, structure, and behavior


Speakers: Al Johnson, Neda Jahanshad, Sofie Valk, Antoine Beauchamp

Chairs: Dr. Clyde Francks and Co-Chair: Dr. Megan Mulligan


HiDiver: Merging Magnetic Resonance and Light Sheet Microscopy with 3D Labels (abstract)
Whole-brain comparison of rodent and human brains using spatial transcriptomics (abstract)
Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex (abstract)
Enhancing Neuro Imaging Genetics through Meta Analysis - Recent GWAS updates and new initiatives from the ENIGMA Consortium (abstract)
Genetic architecture of the white matter connectome of the human brain (abstract)
11:15-12:15 Session 15

Outstanding Travel Awardees

Towards the Neural Basis of Individual Differences in the Exploratory Behavior of Zebrafish (abstract)
The thermo-balancing act: The molecular, cellular, and behavioral mechanisms underlying thermal homeostasis in larval Drosophila (abstract)
Inbred mouse strain differences in adolescent hippocampal learning and gene expression after acute ethanol exposure (abstract)
Behavioral differences in neonatal opioid withdrawal syndrome (NOWS) model phenotypes in FVB substrains following perinatal morphine exposure (abstract)
12:15-13:00Lunch Break
13:00-15:00 Session 16

Symposium 2. Genetic studies of drug addiction-related traits in outbred rats

Speakers: Abe Palmer, Paul Meyer, Hao Chen, Francesca Telese, Alexandria Szalanczy

Chair: Dr. Oksana Polesskaya

Overview of the NIDA center for genetic studies of drug abuse in outbred rats (abstract)
Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders (abstract)
Genome-Wide Association Study Identifies Multiple Loci for Cue-Responsivity Measured During a Pavlovian Conditioned Approach Paradigm. (abstract)
Cell type-specific transcriptional and regulatory mechanisms associated with addiction-related behaviors in HS rats (abstract)
Keratinocyte-associated protein 3 may participate in the stress response to impact adiposity and behavior (abstract)
15:30-17:30 Session 17

Poster Session I

P1 Genetic Variation in Cocaine Preference in the Drosophila melanogaster Genetic Reference Panel (abstract)
P3 Diet and Parent-of-Origin Dependent Effects of Body Composition, Locomotor Activity, and AgRP Neuronal Activity are Sex Specific in PWK/PhJ x C57BL/6J F1 Mice (abstract)
Participation of the neurodevelopmental disorder associated gene MYT1L in motor function and sensory responsivity. (abstract)
P7 Beyond bold versus shy: zebrafish exhibit multiple distinct behavioral types during exploration of a novel tank. (abstract)
P9 Decoding the Role of Synpatically Translated RNA Binding Proteins in Associative Memory (abstract)
P11 Modelling seizure-induced and extinction learning-dependent neuronal activation in pediatric epilepsy (abstract)
P13 Neural circuits for low and moderate alcohol responses in Drosophila melanogaster (abstract)
P15 The relationship between host genetics, microbiome composition and addictive or addictive-predictive behavior in Diversity Outbred mice. (abstract)
P17 The Rat Genome Database (RGD) facilitates neurological disease genes research and cross-species analyses (abstract)
P19 Characterization of novel clinically-relevant behavioral phenotypes in young adult Mucopolysaccharisosis IIIB mice (abstract)
P21 Gene expression profiles in HS-CC founder strains (abstract)
P23 Measuring negative affective withdrawal in CFW mice: Implications for GWAS (abstract)
P25 Interspecific Drosophila Recombinant Inbred Lines as a Tool to Determine Genetic Basis of Neophilia (abstract)
P27 Making data from the Center for GWAS in outbred rats FAIR (abstract)
P29 Effect of Chronic Stress on Inflammation in the hippocampus (abstract)
P31 Investigating the role of Methylglyoxal as a GABAA Agonist through Glyoxalase 1 Manipulation (abstract)
P33 Alcohol-Induced Alternative Splicing in Drosophila Memory Circuits (abstract)
P35 Effects of cocaine on brain and behavior: an evaluation of the fragile X mental retardation protein in dopamine D1 receptor-expressing cells of the striatum (abstract)
P37 Evaluating the convergent evolution of genes associated with pair bonding in mammals (abstract)
P39 The importance of genetic background for model organism genetics, with implications for Alzheimer’s disease and longevity (abstract)
P41 Development of gait abnormalities and tremor in a mouse model of Krabbe disease (abstract)
P43 Exercise Promotes Sex-Specific Resilience to The Effects of Chronic Stress (abstract)
P45 Selecting mice for high cognitive abilities (abstract)
P47 Behavioral differences in neonatal opioid withdrawal syndrome (NOWS) model phenotypes in FVB substrains following perinatal morphine exposure (abstract)
P49 Predicting genotype of fruit flies from locomotive trajectories using supervised Machine Learning (abstract)
Wednesday, May 25th

View this program: with abstractssession overviewtalk overview

08:00-09:00 Session 18

Refreshments and Onsite Registration

09:00-10:00 Session 19

Distinguished Scientist Award

Elissa Chesler

Distinguished Investigator Award Presentation: Dr. Elissa Chesler (abstract)
10:15-12:15 Session 20

Symposium 3. Behavior Quantification using Machine Learning: Challenges and Opportunities

Speakers: Sara Lisanby, Ann Kennedy, Eric Yttri, Vivek Kumar

Chair: Dr. Vivek Kumar

Brain-Behavior Quantification and Synchronization (abstract)
B-SOiD: Automated extraction of meaningful behaviors from any position data without user bias (abstract)
Establishing benchmarks for better behavior quantification (abstract)
Integrated, machine learning based advanced phenotyping platform for the laboratory mouse (abstract)
12:15-13:00Lunch Break
13:00-14:00 Session 21

Young Investigator Award

Dr. Monica Dus

Confection Confusion: the Interplay between diet, genes, and taste (abstract)
14:15-16:15 Session 22

Symposium 4

Selected talks

Rapid Assessment of the Temporal Function and Phenotypic Reversibility of Neurodevelopmental Disorder Risk Genes using Auxin-Inducible Degradation in C. elegans (abstract)
Transcriptional and chromatin-based reprogramming of behaviors with social experience and pheromone signaling (abstract)
The automated social operant task: a quantitative measure of social motivation in mice. (abstract)
Role for the poly r(C)-binding protein 1 (PCBP1) in altered RNA splicing in the hippocampus of rats during withdrawal from chronic ethanol exposure and human subjects with AUD (abstract)
PDZD8 Disruption Causes Cognitive Impairment in Humans and Mice (abstract)
Function of the BN2 neurons in a neural circuit of the adult fruit fly (abstract)
Genetic and non-genetic contributors to behavioral differences among inbred mouse substrains (abstract)
Increased social motivation, motor deficits, and anxiety-like center avoidance in a mouse model of a Williams Syndrome deletion are not the result of Gtf2ird1 expression alone. (abstract)
16:30-18:30 Session 23

Poster Session II

P2 Cell adhesion molecule 2 deletion reduces impulsivity and voluntary cannabinoid intake, and impairs physiological response to THC in mice (abstract)
P4 High Intensity Alcohol Drinking in Mice Leads to Novel Corticostriatal Gene Expression Alterations (abstract)
P6 Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions (abstract)
P8 Effect of Genetic Manipulation of Stress Modulators on Social Interaction in Zebrafish (abstract)
P10 Interactions between neuronal sex determination and Hox gene specification drive the segmental specialization of neural circuits along the anterior-posterior brain axis in Drosophila (abstract)
P12 Interindividual variation in neurological traits in response to early-life Pb exposure (abstract)
P14 RNA-Sequencing in Heterogeneous Stock Mice Selected for Nicotine Preference (abstract)
P16 The role of Drosophila Stat92E signaling in response to repeated alcohol exposures (abstract)
P18 Impact of repeated alcohol exposure on neural STAT signaling activity in Drosophila (abstract)
P20 BALB/cByJ show indiscriminate binge-like eating of both sweetened palatable food and chow compared to BALB/cJ under intermittent, limited access conditions (abstract)
P22 Investigating genetic modifiers of vertebrate stress through genome engineering (abstract)
P24 Daily Binge Drinking Leads to Alterations in Circadian Behavior in C57BL/6J Male and Female Mice (abstract)
P26 A Drosophila model for the role of Williams Syndrome-related factor eIF4H in neural development and behavior (abstract)
P28 Diazepam Effects on Anxiety-related Defensive Behavior of High and Low Open-Field Activity Inbred Mouse Strains (abstract)
P30 A forward genetic screen of ENU-mutagenised zebrafish identifies a mutation co-segregating with impulsivity (abstract)
P32 The methamphetamine-induced hnRNP H targetome identifies CACNA2D2 as a downstream mechanistic target underlying behavior: Pharmacological validation with pregabalin (abstract)
P34 Location-Specific Mutations In CHD7 Induce Specific Sensorimotor Phenotypes In a Zebrafish CHARGE Syndrome Model (abstract)
P36 Both tfbr1b and unkl impact larval zebrafish locomotor responses and may be genetic modifiers of the vertebrate stress response. (abstract)
P38 Characterization of oxycodone use disorder phenotypes in select rat strains of the Hybrid Rat Diversity Panel (abstract)
P40 cyfip2 controls the acoustic startle threshold (abstract)
P42 A reduced complexity cross between BALB/c substrains identifies Zhx2 as a candidate gene underlying oxycodone metabolite brain concentration and state-dependent learning of opioid reward (abstract)
P44 A Pair of Serotonergic Neurons Influence the Circadian Regulation of Short-Term Learning and Memory in Drosophila melanogaster (abstract)
P46 Cocaine withdrawal in the CC/DO founder mouse strains: Interstrain variation and heritability of negative affective withdrawal (abstract)
P48 PKA RIIα Deficiency is Associated with Altered Downstream Expression of Dopamine and Serotonin Signaling Molecules (abstract)
P50 Genetic screen and proteomic analysis: complementary approaches for studying methamphetamine-induced behaviors in D. melanogaster (abstract)
P52 Presynaptic Protein Interaction In Alcohol-Related Behavior In Drosophila (abstract)
P54 Long-term effects of adolescent nicotine exposure vary by genetic background in learning, anxiety-like phenotypes and nicotine sensitivity. (abstract)
P56 Deploying genetic diversity to explore the impact of diet-induced obesity on AgRP neuronal activity (abstract)
P58 Increased social motivation, motor deficits, and anxiety-like center avoidance in a mouse model of a Williams Syndrome deletion are not the result of Gtf2ird1 expression alone. (abstract)
P60 The automated social operant task: a quantitative measure of social motivation in mice. (abstract)
Thursday, May 26th

View this program: with abstractssession overviewtalk overview

08:00-09:00 Session 24

Refreshments and Onsite Registration

08:15-08:45 Session 25

ExComm Meeting

09:00-10:00 Session 26

Presidential Lecture

Dr. Arpana Agarwal

Genome-wide Association Studies and the Gene-Brain-Behavior Pathway to Addiction (abstract)
10:15-12:15 Session 27

Symposium 5. Revolutionary genomics: Third-generation sequencing and pangenome approaches to understanding genes and behavior

Speakers: Thomas Keane, Laura Saba, Tomas Fitzgerald, and Erik Garrison

Chair: Dr. David Ashbrook

Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel (abstract)
Mapping transcriptome structure diversity in rat brain and liver using single molecule RNA sequencing (abstract)
Pangenomes from many points of view (abstract)
New era of mouse genomics with a plurality of reference genomes (abstract)
Iterative ATAC-seq (assay for transposase-accessible chromatin) to home in on neurons regulating behavior. (abstract)
12:15-13:00Lunch Break
12:15-13:15 Session 28

Business Meeting and Lunch

Friday, May 27th

View this program: with abstractssession overviewtalk overview

08:00-09:00 Session 29

Refreshments and Onsite Registration

09:00-11:00 Session 30

Symposium 6. Revealing the function of sleep from flies to humans

Speakers: Paul Shaw, Maxime Jan, Malcolm von Shantz, Nirinjini Naidoo

Chair: Dr. Rozi Andretić and Co-Chair: Dr. Kristin Hamre

Symposium: Revealing the function of sleep from flies to humans (abstract)
Cellular stress and behavior, role of the UPR in sleep and cognition (abstract)
Metabolome, transcriptome, and epigenome: the other phenotypes of sleep loss (abstract)
Defining robust sleep phenotypes for human genetic population studies (abstract)
11:15-12:15 Session 31

keynote Speaker

Dr. Susan Ackerman

tRNAs, Ribosome Stalling, and Neuronal Function (abstract)
12:15-13:00Lunch Break
13:00-15:00 Session 32

The Cerebellar Nuclei in the Limelight (at Last)

Speakers: Marylka Yoe Uusisaari, Justus Kebschull, Richard Wingate, Abigail Person

Chair: Dr. Dan Goldowitz

The cerebellar nuclei: setting the stage (abstract)
A deeply conserved cell-type set forms an archetypal cerebellar nucleus (abstract)
The evodevo of cerebellar nuclei: from temporal patterning to autistic spectrum disorder (abstract)
Cerebellar refinement of skilled movements (abstract)


The Jack Robinson Gallery