GBB 2019: GENES, BRAIN AND BEHAVIOR 2019
PROGRAM

Days: Friday, May 10th Saturday, May 11th Sunday, May 12th Monday, May 13th Tuesday, May 14th

Friday, May 10th

View this program: with abstractssession overviewtalk overview

09:00-16:00 Session 1: Symposium/Workshop

Symposia/Workshop presented by the Simons Initiative for the Developing Brain

18:00-19:00 Session 4: Keynote

Special Lecture

Dr Carmen Sandi

 

Chair:
18:00
Mitochondrial function in the nucleus accumbens links anxiety with stress coping behaviors (abstract)
Saturday, May 11th

View this program: with abstractssession overviewtalk overview

09:00-11:00 Session 6: Symposium 1

Genetics & neurobiology of disordered eating

 

09:00
Elucidation of Secretin in thirst regulation within subfornical organ neurons in the brain (abstract)
09:20
Forward genetic and gene validation studies of binge-like eating in mice: Sex-sensitive genetic loci, including male-specific linkage with the Tas2r locus (abstract)
09:45
Dopamine D2 receptor overexpression in the nucleus accumbens core indirect pathway increases activity-based anorexia selectively in female mice (abstract)
10:10
Taste reward circuitry in women remitted from anorexia nervosa and bulimia nervosa: hunger, satiety, and the motivation to eat (abstract)
10:35
Genome-wide association study of anorexia nervosa implicates metabolic and psychiatric origins (abstract)
11:00-11:30Coffee Break
11:30-12:30 Session 7: Outstanding Travel Awardees

Outstanding Travel Awardees

11:30
CLIP-seq analysis of the RNA binding protein hnRNP H in striatum following methamphetamine administration in Hnrnph1+/- mice (abstract)
11:50
Amygdala NPY circuits are critical for the development of accelerated obesity under chronic stress (abstract)
12:10
Alcohol causes lasting transcriptomic changes in the Drosophila mushroom body (abstract)
12:30-13:30Lunch Break
13:30-15:30 Session 8: Symposium 2

Laterality and cognition

13:30
Colony-level lateralisation of forelimb movements in wood ants (abstract)
14:00
Handedness and neurodevelopmental disorders: a genetic approach (abstract)
14:20
Behavioral laterality predicts fear avoidance responses but does not predict anxiety-related behavior in zebrafish (Danio rerio) (abstract)
14:40
Fish as animal models to explore the relation between anatomical and functional asymmetries (abstract)
15:00
Spontaneous and light induced brain lateralization of c-Fos expression in the newly-hatched chick (abstract)
15:20
What is the role of new-neurons in the development of individual behaviour? (abstract)
15:30-17:30 Session 9: Poster Session

Poster Session I 

Odd Number Posters

15:30
P1 – Reward sensitivity in Hnrnph1+/- mice following acute methamphetamine administration as measured via intracranial self-stimulation (abstract)
15:30
P3 – Role of epigenetic mechanisms in intergenerational effects of anesthesia with sevoflurane in young adult rats (abstract)
15:30
P5 – The Role of Glutamate-related Proteins in Genetic Risk for High Methamphetamine Intake (abstract)
15:30
P7 – Light duration changes locomotor response dependence on HPA axis signaling (abstract)
15:30
P9 – Molecular and neural mechanisms of alcohol-induced sleep disruption in Drosophila (abstract)
15:30
P11 – Transcriptomic analysis of differential treatment of Qi-dysregulation phenotypes revealed the participation of neuroengery in depression using Balb/cJ mouse strain (abstract)
15:30
P13 – Examining the Association Between Polygenic Risk Scores for Neuroticism and Extraversion, Cognitive Biases and Psychopathology Among Adolescents (abstract)
15:30
P15 – Different social behavior and oxytocin responses to acute methamphetamine treatment in juvenile female rats perinatally exposed to stress and/or drug administration (abstract)
15:30
P17 – Early-life low-level chronic lead (Pb) exposure alters anxiety-like behavior, but not alcohol intake, in adult C57BL/6J mice (abstract)
15:30
P19 – Longitudinal DNA methylation changes related to reinforcement psychopathology in adolescence (abstract)
15:30
P21 – Forced swim test and CB-1 receptor expression in hippocampus of offspring of obese male mice (abstract)
15:30
P23 – The Adult Neurogenesis Map (abstract)
15:30
P25 – The role of ErbB3 binding protein 1 (EBP1) in brain development and gene silencing control in mice (abstract)
15:30
P27 – Functional characterisation of ADHD-associated gene variants using the zebrafish as an animal model (abstract)
15:30
P29 – Natural polymorphism in protein kinase G modulates functional senescence in D. melanogaster (abstract)
15:30
P31 Using C. elegans social behaviour to investigate genes associated with autism spectrum disorder (abstract)
Sunday, May 12th

View this program: with abstractssession overviewtalk overview

09:00-11:00 Session 11: Symposium 3

Genes-environment interactions in brain and behavior

 

Chair:
09:00
Learning is enhanced by tailoring instruction to individual genetic differences (abstract)
09:30
Individual differences govern cocaine-related neurobehavioral phenotypes (abstract)
10:00
Using a population-based mouse model for assessment of neurotoxicity in response to early-life lead exposure (abstract)
10:30
Gene-Environment Interactions in Neurotoxicology Research (abstract)
11:00
Gene-by-diet regulation of Alzheimer’s disease pathogenesis (abstract)
11:00-11:30Coffee Break
11:30-12:30 Session 12: Young Investigator Award

Young Investigator Award

Dr. Zoe Donaldson

 

11:30
Functional variation in neuromodulatory genes as a source of behavioral diversity (abstract)
12:30-13:30Lunch Break
13:30-15:30 Session 13: Selected Talks 1

Themed Talks

Mood, Social interactions, cognition and learning.

Chairs:
13:30
Early-life heat exposure influence resilience or vulnerability to heat stress later in life by an epigenetic mechanism (abstract)
13:45
The superior colliculus-mediodorsal thalamus-basolateral amygdala circuit underlies the psychotherapeutic regimen for fear disorders (abstract)
14:00
Kainate receptor auxiliary subunit NETO2 modulates maturity and excitability of amygdala (abstract)
14:15
Using C. elegans social behaviour to investigate genes associated with autism spectrum disorder (abstract)
14:30
Modeling WBS-related gene dosage effects on neuronal and social traits in Drosophila (abstract)
14:45
Neuropeptide modulation of aversion and reward during learning (abstract)
15:00
A forward genetic screen reveals the calcium-sensing GPCR CaSR as a novel modulator of larval sensorimotor decision-making (abstract)
15:15
Genetic and neural circuit analysis of the acoustic startle threshold (abstract)
16:00-17:00 Session 14: Workshop

Professional Development Workshop

Monday, May 13th

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09:00-11:00 Session 16: Symposium 4

Exposure to alcohol or other drugs of abuse during development

 

 

09:00
Symposia Introduction (abstract)
09:10
Effect of Genetics on Neuroinflammatory Responses Following Neonatal Ethanol Exposure in BXD Mice (abstract)
09:35
Choline as a treatment for fetal alcohol spectrum disorders (abstract)
10:10
Behavioural effects of developmental exposure to the synthetic cannabinoid JWH-018 in wild type and disrupted in schizophrenia 1 (DISC1) mutant zebrafish (abstract)
10:30
Conditioned reward following edible ∆9-tetrahydrocannabinol (THC) consumption in adolescent and adult mice (abstract)
10:55
Symposia Discussion (abstract)
11:00-11:30Coffee Break
11:30-12:30 Session 17: Selected Talks 2

Themed Talks

New or improved methodology

11:30
Aberrant vesicular release in mice with a Vamp2 transmembrane mutation underlies striking sleep deficits (abstract)
11:45
Sequencing the BXD family, a cohort for experimental systems genetics and precision medicine (abstract)
12:00
Co-housing affects mouse activity rhythms in a genotype and sex specific manor (abstract)
12:15
Clustering the Spectrum: Finding Genetic Associations for Autism-related Traits (abstract)
12:30-13:30Lunch Break
13:30-14:30 Session 18: Distinguished Investigator Award

Distinguished Investigator Award

Dr. Seth Grant

13:30
Searching for the molecular building blocks of behavior (abstract)
15:30-17:30 Session 20: Poster Session

Poster Session II

Even Number Posters

15:30
P2 – Glucocorticoid receptor dysregulation as a genetic risk factor for high-risk ethanol intake in HDID-1 mice (abstract)
15:30
P4 – The effect of dyslexia candidate genes on reading and language abilities in an adult population cohort (abstract)
15:30
P6 – Low-level embryonic exposure to methylmercury causes neurobehavioral impairment in larval and adult zebrafish (abstract)
15:30
P8 – From sleep to schizophrenia: Investigating the region-specific function of Zfhx3 in the mouse brain, and characterising its molecular activity (abstract)
15:30
P10 – Systematic analysis of brain pH and lactate levels in animal models: relationships and implications for behavioral outcomes (abstract)
15:30
P12 – Ultrasonic communication in the CB1 knockout mouse line during development and at adulthood (abstract)
15:30
P14 – Behavioural characterization of the MDGA2+/- mouse model of Autism spectrum disorder across the lifespan (abstract)
15:30
P16 – ICM-APATHY-TASKS: Developing a New Behavioral Tool to Explore the Three Underlying Mechanisms of Apathy (abstract)
15:30
P18 – The generalized and myoclonic seizures in Krushinsky-Molodkina rat strain (abstract)
15:30
P20 – ADOLESCENT SOCIAL STRESS INFLUENCES MORPHINE SENSITIZATION AND GENE EXPRESSION (abstract)
15:30
P22 – Does tolerance to ethanol-induced sedation explain the sensitized response to ethanol? (abstract)
15:30
P24 – Relative brain weight differences as the result of direct and indirect selection (abstract)
15:30
P26 – Sex Differences in Gene Expression Patterns Associated with the APOE4 Allele (abstract)
15:30
P28 – Heritability of aggression in human: what may be missed and included? (abstract)
15:30
P30 - Ovarian hormones causally contribute to the prophylactic efficacy of (R,S)-ketamine and (2R,6R)-hydroxynorketamine in female mice. (abstract)
15:30
P32 - Neuropeptide modulation of aversion and reward during learning (abstract)
Tuesday, May 14th

View this program: with abstractssession overviewtalk overview

09:00-11:00 Session 22: Symposium 5

Not just insulation: Oligodendrocyte function and myelination in behavior

 

09:00
Myelinated axon plasticity and neural circuit function (abstract)
09:25
Long-lasting molecular and cellular effects of child abuse and depression on oligodendrocyte function (abstract)
09:50
Genetic control of myelin plasticity after chronic psychosocial stress (abstract)
10:15
Catatonia – starting to understand mechanisms involving myelin and neuroinflammation (abstract)
10:40
The developmental trajectory of functional connectivity and sensorimotor behavior in mice (abstract)
11:00-11:30Coffee Break
11:30-12:30 Session 23: Selected Talks 3

Themed Talks

Drugs of abuse and addiction

11:30
Alcohol Related Behaviors in Mice Selectively Bred for High and Low Activity (abstract)
11:45
Glyoxalase 1 involvement in ethanol reward sensitivity and ethanol withdrawal (abstract)
12:00
Genetic differences between BALB/cJ and BALB/cByJ substrains in opioid state-dependent reward learning, spontaneous withdrawal, and weight loss in response to oxycodone: Planting the seeds for a reduced complexity cross (abstract)
12:15
Systems genetic analysis of nicotine withdrawal deficits in learning (abstract)
12:30-13:30Lunch Break
13:30-15:30 Session 24: Symposium 6

Molecules and connected cells

13:30
Genetic dissection of postsynaptic function in behaviour and physiology (abstract)
14:00
Time-course transcriptome created by next-generation sequencing to find coding and non-coding genes involved in cerebellar development and function (abstract)
14:30
Systematic phenomics analysis of ASD-associated genes defines novel shared and unique functions and identifies parallel genetic networks underlying hypersensitivity and impaired habituation (abstract)
15:00
Network topology analysis of the synaptic proteome reveals molecular substructures associated with neurodevelopment, autism and intellectual ability (abstract)
15:30
Developmental disruption of locus coeruleus-norepinephrine signaling results in male-specific behavioral phenotypes relevant to neurodevelopmental disorders (abstract)
15:30-16:00Coffee Break
16:00-17:00 Session 25: Presidential Lecture

Presidential Lecture

Dr. William Schafer

 

16:00
The neuromodulatory connectomes of C. elegans (abstract)
19:30-23:30 Banquet

Banquet Dynamic Earth