Effects of Cranial Irradiation with High-Energy Protons on Visuo-Motor Behaviour in Monkeys

EasyChair Preprint no. 4456

Abstract

In order to model effects of radiation on human central nervous system during long-duration space
flights we investigated instrumental task performance in three irradiated monkeys (Macaca mulatta).
The task mimicked key components of human operator activity. Cranial irradiation with high-energy
protons (170 MeV, 3 Gy) did not result in disturbance of instrumental performance, but hand and eye
movement latencies increased. We propose that disturbance of executive control and attention
systems can account for these results.

Keyphrases: instrumental conditioning, ionizing radiation, non-human primates, protons, saccades

@Booklet{EasyChair:4456,
  author = {Leonid V. Tereshchenko and Lyubov N. Vasileva and Ildar D. Shamsiev and Igor V. Bondar and Evgeniy A. Krasavin and Alexander V. Latanov},
  title = {Effects of Cranial Irradiation with High-Energy Protons on Visuo-Motor Behaviour in Monkeys},
  howpublished = {EasyChair Preprint no. 4456},

  year = {EasyChair, 2020}}