dkNET_DC2022: 2022 dkNET D-Challenge |
Website | https://thesugarscience.org/d-challenge-2022/ |
Submission link | https://easychair.org/conferences/?conf=dknet-dc2022 |
Abstract registration deadline | November 18, 2022 |
Submission deadline | November 30, 2022 |
D-Challenge is a community research challenge designed to increase awareness and use of the rich ecosystem of on-line tools and data findable through dkNET to develop a compelling hypothesis about the biology, treatment, or sequelae of Type 1 Diabetes (T1D). It is open to participants of all skill levels, from students to skilled bioinformaticians and data scientists who have registered by October 1, 2022.
The goal in this challenge is to bring investigators across disciplines to apply their skills and passion to the problem of T1D: its biology, treatment and sequelae, through the use of a rich interconnected ecosystem of data tools and resources. The extensive resources and tools hosted through dkNET provide the opportunity to catalyze searches for novel pathways implicated in disease pathophysiology and / or identify new therapeutic targets. As a partner in the D-Challenge, dkNET provides access to these resources and tools in an easily available setting, fostering discovery by the broad community of investigators focused on T1D.
Entries will be judged on the creative use of public tools, data, and knowledge resources to develop a compelling hypothesis regarding the biology, treatment, or sequelae of T1D. Participants are expected to use multiple on-line tools and platforms and to develop a plan as to how the hypothesis could be tested. The challenge focuses on in-silico development and testing and will not involve a wet lab component. Participants will be organized into different tracts, depending on the amount of bioinformatics experience they have, to ensure that the competition is open to all who are interested in learning about the rich ecosystem of online tools.
Submission Guidelines
D-Challenge Proposal Submission Portal will accept the submissions starting from November 4, 2022. Abstract submission deadline is November 18, 2022. Proposals are accepted until Thursday, November 30, 2022, 5 pm Pacific Time.
EasyChair Abstract Instructions (November 18, 2022, 5 pm Pacific Time):
- Title: Please enter your team name. DO NOT include any information about your hypotheses in your title.
- Abstract: Brief description of your hypothesis that will assist in the selection of reviewers.
- Keywords: just enter "Type 1 Diabetes", "Bioinformatics”, and "D Challenge.”
- Upload: No documents are needed for abstract submission. Submission package (see below) is due November 30, 2022 5 pm Pacific Time.
Submission Package Instructions (November 30, 2022, 5 pm Pacific Time):
- FORMAT: Font: Ariel 11, with half inch margins and single spaced.
- The final proposal should be one (1) PDF document with the sections in the following order:
1. Cover Page: Title of your hypothesis submission, name of D-Challenge team, contact person
2. Section A: Hypothesis Proposal
i. Summary- 30 lines Open science is encouraged but you have the option to protect IP in generalist language
ii. Brief statement of your work that can be shared publicly by the D-Challenge - 3-4 lines in length.
iii. Hypothesis - up to 3 pages
iv. Potential study design -up to 1 page
v. Author list, affiliations, funding acknowledgements - up to 1 page
3. Section B: Protocol from Protocols.io (PDF) - Export to PDF from protocol view page, select the upside down triangle next to the protocol name and then select export to display PDF export option.
4. Section C: Table of resources used, how and when in the process, RRIDs (PDF) [should include: Resource Name, URL/Website, RRID, Use in challenge]. RRIDs can be found for resources at: https://dknet.org/data/source/nlx_144509-1/search
5. Section D: References
6. Section E: Conflict of Interest - i.e. relationship with any of the tools or data used in the Challenge
Partners and Organizers
Partners
- As part of the D-Challenge, a number of partners have provided some starting materials and tutorials to help jump start hypothesis development. We thank our partners:
- Appyters: Introduction; Resource Tutorials
- CalR: Resource Tutorial
- Human Islet Research Network (HIRN): Introduction; Resource Tutorial
- JDRF T1D Fund
- Mouse Metabolic Phenotyping Centers (MMPC): Introduction; Resource Tutorials
- Network for Pancreatic Organ Donors with Diabetes (nPOD)
- Protocols.io
- Pancreatlas: Collection (HPAP, EADB, T1D exocrine); Resource Tutorial
- PANC-DB: Introduction; Resource Tutorials (CellxGene, Data status and download 1, 2)
- Signaling Pathways Project(SPP): Introduction; Resource Tutorials
- Stitchr
- The Adaptive Immune Receptor Repertoire (AIRR): Resource (iReceptor, VDJ Server)
- T1D Knowledge Portal (T1DKP): Introduction; Resource Tutorial
Organizers
Contact
All questions about submissions should be communicated via D-Challenge Slack Platform or D-Challenge@dknet.org.