The entire education system of Ukraine in the realities of the COVID-19 pandemic in 2020 found itself in a situation of challenge for the immediate introduction of distance education in educational institutions of all levels. Despite the presence of a relatively large number of scientific studies on the features of distance education, they were not enough for its practical implementation. Mixed form of learning requires a combination of asynchronous and synchronous modes of distance learning, finding optimal tools and ways to interact with students, adapting traditional methods of studying disciplines to new conditions, overcoming inequality of participants in the educational process in technical support, mastering digital technologies. Analysis of the experience of the Faculty of Physics and Mathematics of G.S. Skovoroda KhNPU showed that the conditions for the introduction of blended learning in institutions of higher pedagogical education are: advanced training and appropriate retraining of teaching staff; building a model of blended learning as a starting point for blended learning; development of educational and methodical support of educational disciplines taking into account the requirements of blended learning; coverage in blended learning of all elements of the educational process; providing participants in the educational process with organizational, methodological, technical and psychological support.