The work undertaken sheds further light on COVID-19 transmission, propagation, and suppression within a community’s sanitation system. the objective of the work is to establish a suitable practical trajectory to be adopted by low-income countries while trying to suppress the spread of the virus during its successive waves (now reaching its fourth phase). The intervening parameters governing the pandemic transmission, growth and suppression, sanitation-water status and relations, health coverage and interactive scenarios for abetment of the virus, UN SDGs level of achievements, national regulations, and country’s vision were of paramount importance in affecting strategic and action health-engineering agenda and plans.

Detection of SARS-CoV-2 genetic materials in wastewater offered an economic and fast technique to detect the presence of the disease in the area and its concentration, which can be used to determine if the disease exceeded the threshold amount from which it makes its way to a majority of residents, resulting in the uncontrolled spread of the illness.