The issue of the training of future teachers of natural and mathematical science to using STEM technologies was discussed on the basis of the system of scientific analysis. The article describes several severities of the process of training future teachers of natural and mathematical science and organization of making use of STEM technologies based on project priorities and application-oriented study methods, connected with modern technologies and also supplying them by social connection in a professional environment. The assembly of the principles of the effectiveness of the training system referred to above shall be defined and described in the following paragraphs.