Brazilian Air Force health team members participating in aeromedical transports of patients with COVID-19 were asked to complete the NASA-TLX questionnaire after the flight, as well as a questionnaire on transport conditions, flight duration, number of patients transported, clinical status of patients, complications and deaths. Transport time was considered as the period from the patient's reception in the ambulance in the runway origin to the moment of transference of the patient to the ambulance in the runway destination. Questionnaires were completed using electronic forms. Each flight condition was evaluated separately, as well as the results to relate the flight characteristics to the reported workload. The health professionals interviewed were: 2 physicians, 2 nurse, 1 physiotherapist and 4 nursing technicians. The average time of the 9 flights evaluated was 4 hours. The results have shown that the effort factor was greater than on longer flight durations, which can be explained by the prolonged use of the PPE used during all missions. The number of transported patients ranged from 1 to 5 and the clinical status also varied between flights, from patients without signs of severity, severe and stable to unstable. Transport with unstable patients showed the highest final weighted rating, in addition to the greatest mental demand and reported frustration. The assessment of mental and physical overload in situations of pandemic and health emergencies is important to understand the limits of the crew and can help to reduce the risks of the operation and provide safer transport conditions. Indeed, this paper has the goal to understand the mental workload risks related to emergency health flight transport, and with it to foster safety and operational risks mitigations for this type of missions, such as resizing health team, work shifts adequations and improving PPE technology.