Bioprocessing resulted in a considerable reduction in energy, water, chemicals, time, and cost requirements. This research explores the influence of pH on combined scouring bleaching of cotton fabric. Several quality parameters, including absorbency, whiteness index, process loss, bursting strength, and dye uptake, were assessed. The results revealed that pH 7.1 performs better in combined scouring bleaching of cotton fabrics. Further research on the optimization of cellulase activity in PAA bleaching with bio-scouring is required.