The current state of digital technologies in domestic business is drastically different from the world’s one. The use of international methodologies to determine the level of digital maturity of business using appropriate indicators is not acceptable for domestic realities due to the low overall level of use of digital technologies in the economic space. The task of developing a national methodology for determining the index of digital maturity of business is relevant and important. Such a methodology should take into account the current state of the national economy, reflect an in-depth analysis of digital maturity indicators of business structures and take into account their dynamics, while being flexible to respond quickly to new economic processes and phenomena, and provide further unification with international methodologies (e.g. DESI). The article analyzes the international approaches to measuring the digital maturity of business structures, and offers its own national methodology for determining the index of digital maturity of business developed on its basis