The authors present a problem of the performance of Unmanned Aerial Vehicles (UAV)’s flight plan group flights for the decision of different tasks in the city (for example, monitoring) using information air navigation technology, graph theory, and mathematical models. The configuration and optimization of group flight routes for UAVs depend on the target tasks. The Algorithm of building Expert System for estimation performance of UAVs flights in smart-town was obtained. Optimization of flight routes for UAVs using dynamic programming methods, GRID analyses, methods of decision making in risk and fuzzy-logic were presented