Bara Basin is one of the most important groundwater basins in west-central Sudan in terms of groundwater availability, water quality and degree of utilization. The basin complex is formed of a number of sub-basins which constitutes the northern extension of the White Nile Rift System and the western extension of the Blue Nile Rift System. Water levels are expected to decline drastically by withdrawals of water from Bara aquifer especially in the vicinity of Al-Sidir wellfield located near Bara town. Further developments in the wellfield are planned to cope with fresh water supply needs of El Obeid City, which raise concerns about the sustainability of the aquifer and the feasibility of its production. Optimization analysis was conducted using USGS’s Groundwater Management Process (GWM) to demonstrate approaches that could be used to evaluate possible future pumping scenarios intended to prolong the productivity of the aquifer and to delay excessive drawdowns. The optimization analyses were based on an existing calibrated groundwater-flow model of Bara aquifer. Two optimization objective functions were formulated, each formulation was set up to maximize total withdrawal rate, subject to withdrawal-rate and hydraulic-head constraints at the location of each well. A user interface was developed for GWM using Visual Basic for Applications programming language (VBA) on MS Excel to ease the utilization of the software. The analysis has shown that pumping of the existing 40 wells in Al-Sidir wellfield at the design capacity (1500 m3/day) will result in a drawdown of 100m in 50-years period. Optimized operation of the wellfield can reduce drawdowns to 50 meters with 31 operating wells at varying pumping rates (Scenario 1), or a 60 meters reduction with 33 operating wells at varying pumping rates (Scenario 2).