School children generally walk to and from school predisposing the occurrence of road traffic crashes in low and middle-income countries. In these countries such as Ghana, Malaysia, and Nigeria pedestrian facilities especially footbridges are provided to minimize pedestrian-vehicle interaction which may result in pedestrian crashes. School children using or not using these footbridges exhibit certain behaviour exacerbating the occurrence of pedestrian crashes. The study aims to investigate how school children use footbridges in Ghana. A total of 8056 school children were observed during a seven-day period in the vicinity of seven footbridges in the Greater Accra (6) and Kumasi (1) Metropolitan areas, Ghana. Five behaviours were observed together (i.e. being accompanied, running, wearing earpieces, carrying a piece of luggage and riding a bicycle) with demographic and contextual factors. Most of the school children who used the footbridges was talking among themselves, wearing an earpiece, or being accompanied. A binary logistic regression was fitted to predict the five behaviours using the demographic and contextual explanatory variables. The results revealed that gender, location of the footbridges, day of the week, time of observations, being accompanied, wearing of the earpiece, carrying a piece of luggage and riding a bicycle were significantly associated with the use of footbridges in Ghana. The findings of this study have significant policy implications for the development of targeted education and footbridge policing.