The article describes the organizational and pedagogical conditions of information and communication technology (ICT) health-saving usage at middle school. The model of realization of named conditions and the model of cooperation of participants of educational process within health-saving use of ICT were developed. The examples and hints of how to implement the organizational and pedagogical conditions of ICT health-saving usage are given. An empirical study showed that in the experimental group that studied under the authors’ conditions, the number of students demonstrated high results in three directions (attention stability and mental capacity, healthy vestibular-motor reactions, positive psycho-emotional state) that are much ahead of those obtained in the control group. Consequently, the obtained data showed the effectiveness of the conditions developed by authors. It is emphasized that the named conditions can be realized only through concentration of efforts and concerted interaction of all parties of the educational process.