NASA’s plans to return humans to the Lunar surface require overcoming a variety of challenging technical and operational obstacles. The Agency has a variety of methods to identify, characterize, and communicate these gaps, and pursues gap closure through industry partnerships and internal R&D. This presentation details spacecraft technology gaps for Computer Human Interfaces, a subset of spacecraft avionics focused on effective and autonomous crew interaction with spaceflight systems. The gaps, grouped into displays, audio systems, and information technology infrastructure, are largely driven by the unique interaction requirements for human systems and the severe radiation environments beyond low earth orbit. The roadmap identifies ongoing technology development activities and technology performance targets to meet mission needs in these areas. NASA is seeking input on the content and ideas for alternative paths to gap closure. Closing these gaps is important to successful human operations on the Lunar surface and vital to NASA’s long-term goal of human missions to Mars.