Program for Sunday, October 9th: Talk View

12:30-13:30 LUNCHEON I: Advancements in single cell multiomic profiling of antigen-specific T cells with dCODE Dextramer® (RiO) on the BD Rhapsody™ Single-Cell Analysis System.

12:30-13:30 LUNCHEON II: Tutorial: Modelling with VCell

13:30-15:30

An integrative understanding of the large metabolic shifts induced by antibiotics in critical

Marfil Sánchez et.al

13:30-15:30

Agent-based modeling of spatiotemporal organization of bacteria in the human gut

Kristiyana Tsenova, Jörg Ackermann, Maria J.G.T. Vehreschild, Ina Koch

13:30-15:30

Microbial compound bioactivity descriptors enable large-scale prediction of small molecule impact on microbiota species and

Nils Kurzawa, Patrick Aloy

13:30-15:30

Towards identification of new life cycle-associated regions in phage genomes using deep learning

Melania Nowicka, Jakub M. Bartoszewicz, Bernhard Y. Renard

13:30-15:30

Computationally Modeling the Human Microbiome of the Respiratory Tract

Andreas Dräger

13:30-15:30

Latent variable models of fungal growth considering the data measurement process

Tara Hameed, Natasha Motsi, Elaine Bignell, Reiko J. Tanaka

13:30-15:30

The metabolic community model of Staphylococcus aureus and four abundant human nasal microbes

Reihaneh Mostolizadeh, Manuel Glöckler, Andreas Dräger

13:30-15:30

GuaCAMOLE: fragment GC bias-aware abundance estimation from metagenomic data increases accuracy and

Laurenz Holcik, Florian Pflug, Arndt von Haeseler

13:30-15:30

Macroecological Laws Naturally Arise from Complex Chaotic Dynamics of Gut Microbiota

Konstantine Tchourine, Martin Carballo-Pacheco, Dennis Vitkup

13:30-15:30

Human host and pathogenic fungi: modeling and deciphering nested metabolic defense strategies

Wassili Dimitriew, Jan Ewald, Stefan Schuster

13:30-15:30

Resistant starch decreases intrahepatic triglycerides in NAFLD patients via the gut microbiome contribution to the branched-chain amino acids

Ni et.al

13:30-15:30

A probabilistic graphical model for taxonomic profiling of viral and microbiome proteome samples

Tanja Holstein, Pieter Verschaffelt, Lennart Martens, Thilo Muth

13:30-15:30

Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise

Alonso-Roman, Schaeuble, Gresnigt, Last, Mirhakkak, Panagiotou, Hube

13:30-15:30

Cell Type view into tomato stem elongation in Shade avoidance response

Linge Li, Ticho Helming, Chrysoula K. Pantazopoulou, Ronald Pierik, Kaisa Kajala

13:30-15:30

Quantitative Impacts of Bumble Bee Ecology on Foraging Behaviour: An Economic Model

Arran Hodgkinson, Katy Chapman, Katie Hall, Sean Rands, Natalie Hempel de Ibarra

13:30-15:30

Discovery of Robust and Highly Specific Microbiome Signatures for Non-Alcoholic Fatty Liver Disease

E. Nychas, A. Marfil Sánchez, X. Chen, Y. Ni, G. Panagiotou

13:30-15:30

From genome sequencing to the first draft of the genome scale metabolic model of the symbiont fungus Leucoagaricus gongylophorus

Castillo Alfonso et.al

13:30-15:30

Effect of dispersal by inundation on soil bacterial communities depends on soil developmental stage

Xiu Jia, Cas Cornet, Joana Falcão Salles

13:30-15:30

In silico analysis of metabolic capabilities in a synthetic community of phycosphere bacteria

Miller Merchant, Jeffrey Kimbrel, Ty Samo, Xavier Mayali, Ali Navid

13:30-15:30

Benchmarking Phage-Host Prediction Tools using Real Metagenomics Data

van Doorn, Wu, Hauptfield, Carillo, Grozdani, Pappas, Dutilh

13:30-15:30

Continuous-time models under uncertainty

Markus Heinonen

13:30-15:30

Path Integral Stochastic Optimal Control for Sampling Transition Paths

Lars Holdijk

13:30-15:30

Posterior marginalization accelerates Bayesian inference for dynamical systems

Elba Raimundez, Michael Fedders, Jan Hasenauer

13:30-15:30

The Economy and Control of Balanced Cellular Growth

Hugo Dourado, Wolfram Liebermeister, Oliver Ebenhöh, Martin Lercher

13:30-15:30

Hybrid mechanistic and deep learning modeling in systems biology

Maren Philipps, Jan Hasenauer

13:30-15:30

Discovery of Hidden Control Variables and modeling Non-Linear Dynamical Biological Systems

Munoz, Balsamy, Bernal Tamayo, Balubaid, Gomez Cabrero, Kiani, Tegner

13:30-15:30

Combining machine learning and ODE’s to build multiscale models for estimation of metabolic

Natal van Riel, Bert Groen

13:30-15:30

Linking models of biochemical dynamics via mass-constrained neural ordinary differential equations

Domas Linkevicius, Melanie Stefan, Angus Chadwick, David C. Sterratt

13:30-15:30

Reinforcement learning and Monte-Carlo tree search in gene expression enable the entire gene regulation in a

Tomoyuki Yamaguchi

13:30-15:30

Efficient parameter estimation for ODE models with semi-quantitative data using spline approximation

Domagoj Doresic, Jan Hasenauer, Stephan Grein

13:30-15:30

Hybrid models for cellular signaling: meso-scale pathway identification

Jorge Alberto Guzmán Maldonado, Andreas Schuppert

13:30-15:30

On data-driven learning of an effective energy landscape from trajectories of nonlinear dynamical biological

S. Saha, S. A. Khan, A. O. Balubaid, D. Gomez-Cabrero, N. A. Kiani, J. N. Tegner

13:30-15:30

Structural reduction of chemical reaction networks based on topology

Yuji Hirono, Takashi Okada, Hiroyasu Miyazaki, Yoshimasa Hidaka

13:30-15:30

Directed cell migration by cortical actin and ER-PM contact site-mediated restriction of receptor signaling to the

Tobias Meyer, Bo Gong, Alex Thiemicke

13:30-15:30

Regulation of Mammalian Iron Physiology Across Scales

Pedro Mendes

13:30-15:30

Modelling how mRNA flows through subcellular compartments

David Steinbrecht, Nils Blüthgen

13:30-15:30

Spatio-temporal modeling reveals a layer of tunable control circuits for the distribution of cytokines in

Patrick Brunner, Lukas Kiwitz, Kevin Thurley

13:30-15:30

Real-time biochemical computations at criticality

Aneta Koseska

13:30-15:30

Stochasticity of Meiotic Entry in Xenopus Oocytes

Deniz Fettahoglu, Charbel Choufani, Anna Castro, Thierry Lorca, Ovidiu Radulescu

13:30-15:30

Rhythmic protein degradation for cost-effective circadian oscillation

Cheol-Min Ghim, Junghun Chae

13:30-15:30

Model-based design of a synthetic oscillator based on an epigenetic memory system

Viviane Klingel, Dimitri Graf, Sara Weirich, Albert Jeltsch, Nicole Radde

13:30-15:30

Advanced Modelling of Multicellular Systems in Morpheus

Jörn Starruß, Diego Jahn, Lutz Brusch

13:30-15:30

Resolving Resolution Hindrances in Spatial Transcriptomics

Connor King, Brendan Podell, Sarah Cooper

13:30-15:30

Inferring individual interactions in gene regulatory networks with delays from time-series

Yu Wang, Elling Jacobsen

13:30-15:30

Variance of filtered signals: characterization for linear reaction networks and application to neurotransmission

Ariane Ernst, Christof Schütte, Stephan Sigrist, Stefanie Winkelmann

13:30-15:30

Dynamical basis of cellular sensing and responsiveness to spatial-temporal signals

Akhilesh Padmanabhan Nandan, Aneta Koseska

13:30-15:30

Computational modeling of the Hes1 oscillator for the self-renewal of muscle stem cells

Z. Bujtár, K. Baum, Y. Zhang, I. Lahmann, C. Birchmeier, J. Wolf

13:30-15:30

A powerful modelling approach tailored to cellular signalling

Rafael Arutjunjan, Emilia Neuwirt, Svenja Wöhrle, Olaf Groß, Clemens Kreutz

13:30-15:30

A robust model of neural superposition sorting

Eric Reifenstein, Egemen Agi, Peter Robin Hiesinger, Max von Kleist

16:00-16:45

Machine learning for hard biological problems

Chris Sander

16:45-19:30

FitMultiCell: Simulating and parameterizating computational models of multi-cellular processes

Emad Alamoudi, Jan Hasenauer, Joern Starruß, The Fitmulticell Consortium

Transcriptional fluctuations govern the serum dependent cell cycle duration heterogeneities in Mammalian

Vinodhini Govindaraj, Subrot Sarma, Atharva Karulkar, Rahul Purwar, Sandip Kar

Benchmarking of analysis strategies for data-independent acquisition proteomics data

Eva Brombacher, Klemens Fröhlich, Oliver Schilling, Clemens Kreutz

A generic framework to coarse-grain stochastic reaction networks by Abstract Interpretation

Albin Salazar, Jerome Feret

Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human

Sae-Ong, Barber, Kang, Seelbinder, Li, Walther, Kurzai, Panagiotou

Tissue-specific codon usage: from systems to synthetic biology

Xavier Hernandez-Alias, Hannah Benisty, Luis Serrano, Martin H. Schaefer

A Systems Biology Approach To Study The Spatiotemporal Dynamics Of Senescent Cells In Wound Healing And Tissue

Sharmilla Chandrasegaran

Impact of Amyloid-Beta Induced Disruption on Ca2+ Homeostasis in a Simple model of Neuronal Activity

Francisco Prista von Bonhorst, Geneviève Dupont

Improving Our Understanding of ADPKD: Computational Analysis of Metabolome Data

Hande Özge Aydoğan, Philipp Antczak, Roman-Ulrich Müller

Molecular principles governing substrate specificity of human SUMO E3 Ligases

Alberto Cristiani, Arghya Dutta, Ramachandra M. Bhaskara

A mechanistic model for endocrine profiles of female puberty maturation

Sophie Fischer-Holzhausen, Susanna Roeblitz

Advanced Modelling of Multicellular Systems in Morpheus

Jörn Starruß, Diego Jahn, Lutz Brusch

Resistant starch decreases intrahepatic triglycerides in NAFLD patients via the gut microbiome contribution to the branched-chain amino acids

Ni et.al

Data-driven mathematical modeling of human skin aging and its application for natural compound

Masatoshi Haga, Tsuyoshi Ishii, Mariko Okada

Information Processing by Homo-Oligomeric Proteins: From First Principles to Cardiac Disease

Daniel Koch

Modeling the adaptive immune response of a lymph node as Petri net

S. Scharf, P. Wurzel, H. Schäfer, J. Ackermann, M.-L. Hansmann, I. Koch

Resolving Resolution Hindrances in Spatial Transcriptomics

Connor King, Brendan Podell, Sarah Cooper

Digital twins and hybrid modelling for simulation of physiological variables and stroke risk

T. Herrgårdh, E. Hunter, K. Tunedal, J.D. Kelleher, G. Cedersund

Dynamical basis of cellular sensing and responsiveness to spatial-temporal signals

Akhilesh Padmanabhan Nandan, Aneta Koseska

Identification of causal genes at GWAS loci with pleiotropic gene regulatory effects using instrumental variable

Mariyam Khan, Adriaan Ludl, Sean Bankier, Tom Michoel

A model of RNA repair to study antibiotic tolerance

Hollie Hindley, Andrea Weiße, Meriem El Karoui

Insights on hemodynamic changes in hypertension and T2D through non-invasive cardiovascular modeling

K. Tunedal, C.-J. Carlhäll, F. Viola, T. Ebbers, G. Cedersund

COVRECON: Combining Genome-scale Metabolic Network Reconstruction and Data-driven Inverse Modeling to Reveal Causal Biochemical

Jiahang Li, Steffen Waldherr, Wolfram Weckwerth

Lipid metabolic reprogramming extends beyond histological tumor demarcations in human operable pancreatic

Pirhonen et.al

Non-parametric model-based estimation of the effective reproduction number for SARS-CoV-2

Jacques Hermes, Christian Tönsing, Marcus Rosenblatt, Jens Timmer

Federated mathematical modelling and machine learning for a multi-national cohort of COVID-19

Manuel Huth, Jan Hasenauer, Roy Gusinow

Integrative analysis on comorbid signatures in psychotic disorders using multi-rank non-negative matrix factorization based graph

Youcheng Zhang, Carl Herrmann

The pharmaco-epigenomic landscape of cancer cell lines reveals the epigenetic component of drug

A.J. Ohnmacht, A.R. Rajamani, G. Avar, G. Kutkaite, M.P. Menden

Manually curated genome-scale metabolic reconstructions of the multi-drug resistant Gram-negative pathogens A. baumannii and K.

Nantia Leonidou, Meike Lips, Yufan Xia, Andreas Dräger

Single cell analysis of colorectal cancers with familial adenomatous polyposis for revealing differential pre-malignant

Najung Lim, Jonghyun Lee, Dongkwan Shin

A deep learning-based approach for counting ovarian follicles

Misbah Razzaq, Maya Haj-Hassan, Eric Reiter

Modeling disease progression in spinocerebellar ataxias

Elisabeth Georgii, Marie Piraud, Jennifer Faber

Computational modeling of the Hes1 oscillator for the self-renewal of muscle stem cells

Z. Bujtár, K. Baum, Y. Zhang, I. Lahmann, C. Birchmeier, J. Wolf

Learning synthetic cell classifier designs with genetic algorithms and logic programming

Melania Nowicka, Heike Siebert

Machine learning-based prediction of frailty in elderly people - Data from the Berlin Aging Study-II

Didier, De Landtsheer, Pires Pacheco, Kishk, Schneider, Demuth, Sauter

M4-health: digital twins that follow you throughout your health journey

Gunnar Cedersund, Henrik Podéus

Multi-platform model training reduces bias in translational drug sensitivity models for cancer

Lisa-Katrin Schätzle, Andreas Schuppert

Quantify the role of DMT1 endocytosis, IRPs activity, and FT iron sequestration in duodenal enterocyte iron

Joseph Masison, Pedro Mendes

Periodic Forcing of the ERK pathway

Nguyen Tran, Andrew Clayton

Jinkō Knowledge: An integrated knowledge management tool prior to in silico multiscale model

S. Martis B, C. Monteiro, T. Bourlier, J. Ponchon, J.-P. Boissel

Deciphering dysregulation in Erythroleukemia to design intervention strategies

Abdullah, Bang, Li, Motzfeldt, Helm, Gjertsen, Schilling, Timmer, Klingmüller

The insidious trappings of gene set enrichments

January Weiner

Predicting metabolite accumulation in cancerous metabolic network

Tin Yau Pang, Martin Lercher

Patient-specific modeling of the TP53 pathway in endometrial carcinoma patients

Oscar Arturo Migueles Lozano, Fabian Konrath, Katharina Baum, Jana Wolf

The abundance and cross-talk of EGFR and MET receptors in lung cancer cell lines is critical for the efficacy of tyrosine kinase

Frey et.al

Alterations in hepatocyte growth factor induced signal transduction in fatty liver disease foster cancer

Biermayer et.al

Inferring individual interactions in gene regulatory networks with delays from time-series

Yu Wang, Elling Jacobsen

Multilevel approach characterizing the progression of fatty liver disease

Biermayer et.al

A generic approach to decipher the mechanistic pathway of heterogeneous protein aggregation kinetics

Baishakhi Tikader, Samir K. Maji, Sandip Kar

Dynamic fluctuations in a bacterial metabolic network

S. Bi, M. Kargeti, R. Colin, N. Farke, H. Link, V. Sourjik

The role of the kynurenine metabolism in chronic graft-versus-host-disease: Insights from computational modeling and patient

T. Stiehl, L. Orsatti, R. Speziale, P. Di Pasquale, E. Monteagudo, T. Luft

Mechanistic insights into sensitization and desensitization of the Interferon α signal transduction

M. Rosenblatt, F. Kok, M. Teusel, M. Schilling, U. Klingmüller, J. Timmer

Fast parameter estimation for ODE-based models of heterogeneous cell populations

Yulan van Oppen, Andreas Milias-Argeitis

Dynamic analysis framework to detect cell division and cell death in live-cell imaging, using signal processing and machine

Asma Chalabi, Eric Debreuve, Jérémie Roux

Quantification of bacterial resource allocation in changining environments on the single-cell level

Antrea Pavlou, Hidde de Jong, Hans Geiselmann, Eugenio Cinquemani

A robust model of neural superposition sorting

Eric Reifenstein, Egemen Agi, Peter Robin Hiesinger, Max von Kleist

Decoding cellular deformation from pseudo-simultaneously observed RhoGTPase activities

Katsuyuki Kunida, Yuichi Sakumura

Amino Acid Impact on Protein Secretion in B. subtilis: an RBA Approach

Rafael Moran, Jan Maarten Van Dijl, Edda Klipp

Phylogeny and artificial neural networks

Leuchtenberger, Crotty, Drucks, Schmidt, Burgstaller-Muehlbacher, von Haeseler

Discovery of Robust and Highly Specific Microbiome Signatures for Non-Alcoholic Fatty Liver Disease

E. Nychas, A. Marfil Sánchez, X. Chen, Y. Ni, G. Panagiotou

Building the knowledge base to understand cellular signal transduction in different inflammatory

Marcus Krantz, Robert Kruse, Eva Särndahl, Katarina Persson

Macroecological Laws Naturally Arise from Complex Chaotic Dynamics of Gut Microbiota

Konstantine Tchourine, Martin Carballo-Pacheco, Dennis Vitkup

Boolean dynamic modeling of TNFR1 signaling predicts a nested feedback loop regulating the apoptotic response at single-cell level (EXCEPTION -

Shubhank Sherekar, Ganesh Viswanathan

Frequency preference in miRNA-mRNA interaction models: competition and cooperativity effects

Candela Szischik, Elsi Ferro, Carla Bosia, Alejandra C. Ventura

Coordination of p53 and MAPK dynamics controls heterogeneous responses to genotoxic agents in single

Eric Batchelor

Explainable Machine Learning in Mass Spectrometry-based Proteomics

Tom Altenburg, Thilo Muth, Bernhard Y. Renard

Logical modeling of signaling mechanisms in early development

Yozlem Bahar, Alisa Fuchs, Kirsten Thobe, Robert Patrick Zinzen, Jana Wolf

Multi-dimensional immune correlates of early prediction of COVID-19 severe versus asymptomatic disease

Holetschek et.al

Hybrid models for cellular signaling: meso-scale pathway identification

Jorge Alberto Guzmán Maldonado, Andreas Schuppert

Gene-essentiality based drug signature helps repurposing non-cancer drugs

Wenyu Wang, Jing Tang

Elucidating the role of TAS2R43 in HGT-1 cells – an integrated omics approach

Behr et.al

Dynamics of the circadian clock in models of cancer and its potential for treatment

Carolin Ector, Christoph Schmal, Adrián E. Granada

Identification of personalised driver gene panels in Melanoma

Shrisruti Sriraman, Nagasuma Chandra

Inference of differential gene regulatory networks from gene expression data using boosted differential

Gihanna Galindez, Markus List, Jan Baumbach, David B. Blumenthal, Tim Kacprowski

Initial source of heterogeneity in a model for cell fate decision in the early mammalian embryo

C. Robert, F. Prista von Bonhorst, G. Dupont, Y. De Decker, D. Gonze

Exact Confidence Regions for Non-Linear Models

Rafael Arutjunjan, Björn Malte Schäfer, Clemens Kreutz

Towards rational design of antibiotic combination therapies

Elena Pascual Garcia, Andrea Weiße, Charlotte Kloft, Wilhelm Huisinga

Combining single-cell imaging techniques to probe surface-adhesion-dependent morphological features of disease

Matthew Lux, Dominic Jenner

Network-based Stratification of Cancer Drugs

Seyma Unsal Beyge, Nurcan Tuncbag

Deep learning a model of cytotoxic T cell activation in the tumor microenvironment

M. Wahlsten, A. Akhshi, S. Achar, A. Krishnan, P. François, G. Altan-Bonnet

Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise

Alonso-Roman, Schaeuble, Gresnigt, Last, Mirhakkak, Panagiotou, Hube

Nonstationary Biomedical Signal Feature Extraction

Sri Krishnan

Reconstruction of regulatory networks driving patterned expression in the Drosophila embryo based on spatially resolved single-cell sequencing

Miriam Faxel

Improving our Mechanistic Understanding of Cell Cycle Dynamics

Paul Lang, David Penas, Julio Banga, Daniel Weindl, Bela Novak

A graph-based approach to analyze signal transduction involving cytokines and the JAK-STAT pathway in hepatocytes using Petri

Marcus Keßler, Jörg Ackermann, Heiko Mühl, Christoph Welsch, Ina Koch

A Reproducibility Scorecard for Self-checking of Systems Biology Models

R. Sheriff, K. Tiwari, T. Nguyen, D. Waltemath, H. Hermjakob

BioModels: an open repository of mathematical models of the biological and biomedical processes

Tung V. N. Nguyen, Krishna Tiwari, Henning Hermjakob, Rahuman S Malik Sheriff

Metabolic profile predictions using efficient and interpretable data descriptors generated with relational

Daniel Brunnsåker, Filip Kronström, Ievgeniia Tiukova, Ross King

Model-based design of a synthetic oscillator based on an epigenetic memory system

Viviane Klingel, Dimitri Graf, Sara Weirich, Albert Jeltsch, Nicole Radde

Structural reduction of chemical reaction networks based on topology

Yuji Hirono, Takashi Okada, Hiroyasu Miyazaki, Yoshimasa Hidaka

Combined multiple transcriptional repression mechanisms generate ultrasensitivity and oscillations

Eui Min Jeong, Yun Min Song, Jae Kyoung Kim

Multi-Omics Visible Drug Activity prediction, interpreting the biological processes underlying drug

L. Ferraro, S. Giovanni, M. Ceccarelli, R. Mall, E. Carosati

DUNE-COPASI: Multi-Compartment Diffusion-Reaction solver for Cell Biology

S. Ospina De Los Rios, P. Bastian, L. Keegan, U. Kummer, S. Sahle

Computational modeling of DLBCL predicts response to BH3-mimetics

Cloete, Smith, Jackson, Pepper, Pepper, Vogler, Dyer, Mitchell

Automated detection and regional classification of Cerebral Amyloid Angiopathy in digital whole slide

Minaud et.al

Cell type-specific gene co-expression modules define tumor heterogeneity in melanoma patients

Lars Bosshard, Michael Prummer

Universality of form: The case of retinal cone photoreceptor mosaics

Alireza Beygi

Dimethyl fumarate shifts CSF protein profile in relapsing remitting MS: a proteomics approach for biomarker

S. Hojjati, J. Ernerudh, M. Vrethem, J. Mellergård, J. Raffetseder

Automated improvement of genome-scale models using a first-order logical model of metabolism

A. Gower, K. Korovin, D. Brunnsåker, I. Tiukova, R. King

The potential of PBI for high resolution lung imaging in patients

Dullin et.al

Cohort-specific Boolean models highlight different regulatory modules during disease progression

Ahmed Hemedan, Reinhard Schneider, Marek Ostaszewsk

A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and

Knudsen, Hamilton, Proks, Lykkegaard, Nielsen, Trusina, Brickman

A comprehensive mechanistic model of adipocyte signaling with layers of confidence

W. Lövfors, C. Jönsson, C.S. Olofsson, G. Cedersund, E. Nyman

Hierarchical gene function prediction using a novel topology-based threshold and comparing 6 correlation metrics. Study case:

Nicolas Antonio López Rozo, Miguel Romero, Jorge Finke, Camilo Rocha

Personalized medicine for Multiple Sclerosis treatment strategies at the individual and population

Fianne Sips, Alberto Palazzin, Roberta Bursi

Deciphering transcriptional drivers of stem cell differentiation using causal inference

M. Proks, J.A. Romero, T.E. Knudsen, A. Trusina, J. Sedzinski, J.M. Brickman

In silico analysis of metabolic capabilities in a synthetic community of phycosphere bacteria

Miller Merchant, Jeffrey Kimbrel, Ty Samo, Xavier Mayali, Ali Navid

GO Term-based Comparative Functional Genomics in Plants

Dennis Psaroudakis, Leila Fattel, Carolyn J. Lawrence-Dill

Exploring the missing heritability in SPG7 heterozygous carriers with Whole Genome Sequencing

Coutelier, Méreaux, Guillaud-Bataille, Guillot-Noël, Davoine, Brice, Durr

Comparative analysis of molecular fingerprints in prediction of drug combination effects

Bulat Zagidullin, Ziyan Wang, Yuanfang Guan, Esa Pitkänen, Jing Tang

Proteomics profiling revealed a combination of protein biomarkers for predicting disease trajectory of multiple

Åkesson et.al

Linking models of biochemical dynamics via mass-constrained neural ordinary differential equations

Domas Linkevicius, Melanie Stefan, Angus Chadwick, David C. Sterratt

Data-driven modeling of mitochondrial metabolism

Polina Lakrisenko, Andre Wegner, Daniel Weindl, Tobias Ludwig, Nils Krause

Quantitative Impacts of Bumble Bee Ecology on Foraging Behaviour: An Economic Model

Arran Hodgkinson, Katy Chapman, Katie Hall, Sean Rands, Natalie Hempel de Ibarra

Dynamic single cell analysis of a MAPK signaling cascade and its impact on transcriptional output

Guilaume Lieb

Targeted Proteomics-Driven Computational Modeling of the Mouse Macrophage Toll-like Receptor Signaling

Manes et.al

Latent Dirichlet Allocation for Double Clustering (LDA-DC): Discovering patients phenotypes and cell populations within a single Bayesian

Elie-Julien El Hachem, Nataliya Sokolovska, Hédi Soula

Combinatorial effects of ligands are predicted by a genome-scale model of signaling based on artificial neural

A. Nilsson, J.M. Peters, N. Meimetis, B. Bryson, D.A. Lauffenburger

Agent-based modeling of spatiotemporal organization of bacteria in the human gut

Kristiyana Tsenova, Jörg Ackermann, Maria J.G.T. Vehreschild, Ina Koch

Scalable and flexible inference framework for stochastic dynamic single-cell models

Sebastian Persson, Marija Cvijovic, Umberto Picchini

Stochastic Model of Intra-Tumor Heterogeneity (SMITH)

Adam Streck, Tom Kaufmann, Roland F. Schwarz

Temporal Proteomics and Transcriptomics Unravels the Host-Pathogen Interaction Network of Macrophages and Corynebacterium

Luca Musella, Jens Moeller, Lisa Baeumer, Julio Vera, Andreas Burkovski

Lineage plasticity in prostate cancer depends on FGFR and JAK/STAT inflammatory signaling

Chan et.al

Efficient parameter estimation for ODE models with semi-quantitative data using spline approximation

Domagoj Doresic, Jan Hasenauer, Stephan Grein

10:00-10:30 Coffee Break

15:30-16:00 Coffee Break